دورية أكاديمية

Risk factors and prediction model for postoperative complications in patients with struvite stones after percutaneous nephrolithotomy and flexible ureteroscopy.

التفاصيل البيبلوغرافية
العنوان: Risk factors and prediction model for postoperative complications in patients with struvite stones after percutaneous nephrolithotomy and flexible ureteroscopy.
المؤلفون: Tian C; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., Qiao J; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., An L; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., Hong Y; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., Xu Q; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., Xiong L; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., Huang X; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China., Liu J; Department of Urology, Peking University People's Hospital, 11 Xizhimen South Street, Xicheng District, Beijing, 100034, People's Republic of China. hmuliujun@163.com.; Peking University Applied Lithotripsy Institute, Peking University, Beijing, 100034, People's Republic of China. hmuliujun@163.com.
المصدر: World journal of urology [World J Urol] 2024 Sep 02; Vol. 42 (1), pp. 501. Date of Electronic Publication: 2024 Sep 02.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8307716 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-8726 (Electronic) Linking ISSN: 07244983 NLM ISO Abbreviation: World J Urol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Berlin ; New York] : Springer International, 1983-
مواضيع طبية MeSH: Nephrolithotomy, Percutaneous*/adverse effects , Nephrolithotomy, Percutaneous*/methods , Postoperative Complications*/etiology , Postoperative Complications*/epidemiology , Postoperative Complications*/diagnosis , Ureteroscopy*/adverse effects , Kidney Calculi*/surgery , Struvite* , Nomograms*, Humans ; Female ; Retrospective Studies ; Middle Aged ; Male ; Risk Factors ; Adult ; Aged ; Risk Assessment
مستخلص: Objective: To analyze the risk factors for complications in patients with struvite stones following percutaneous nephrolithotomy (PCNL) or flexible ureteroscopy (fURS), and to establish a nomogram for postoperative complications in patients following PCNL.
Methods: A retrospective analysis was conducted on patients with struvite stones after PCNL and fURS at the Department of Urology, Peking University People's Hospital, from January 2012 to March 2022. The common pathogens and antimicrobial susceptibilities in preoperative midstream urine culture were analyzed. Logistic regression analyses were used to evaluate the risk factors. Receiver-operating characteristic (ROC) curve, calibration plots, and decision curve analysis (DCA) were used to assess the discrimination, accuracy, and practicability of the nomogram.
Results: 332 patients with struvite stones received one-stage PCNL or fURS, including 243 cases of PCNL and 89 cases of fURS. 72 patients (21.69%) developed postoperative complications. The most common pathogens in preoperative urine cultures were Escherichia coli, Proteus mirabilis, and Enterococcus faecalis. Multivariate logistic regression analysis showed that preoperative hemoglobin (OR = 0.981, P = 0.042), staghorn stone (OR = 4.226, P = 0.037), and positive preoperative midstream urine culture (OR = 2.000, P = 0.043) were independent risk factors for postoperative complications in patients following PCNL. The nomogram showed good performance in discrimination, accuracy, and applicability.
Conclusion: Preoperative hemoglobin, staghorn stone, and positive preoperative midstream urine culture were independent risk factors for postoperative complications in patients with struvite stones following PCNL. A nomogram was developed to predict the probability of postoperative complications.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
References: Flannigan R, Choy WH, Chew B et al (2014) Renal struvite stones–pathogenesis, microbiology, and management strategies. Nat Rev Urol 11(6):333–341. (PMID: 10.1038/nrurol.2014.9924818849)
Bichler KH, Eipper E, Naber K et al (2002) Urinary infection stones. Int J Antimicrob Agents 19(6):488–498. (PMID: 10.1016/S0924-8579(02)00088-212135839)
Koras O, Bozkurt IH, Yonguc T et al (2015) Risk factors for postoperative infectious complications following percutaneous nephrolithotomy: a prospective clinical study. Urolithiasis 43(1):55–60. (PMID: 10.1007/s00240-014-0730-825269441)
Singh AK, Shukla PK, Khan SW et al (2018) Using the modified Clavien grading system to classify complications of percutaneous nephrolithotomy. Curr Urol 11(2):79–84. (PMID: 10.1159/00044719829593466)
Seymour CW, Liu VX, Iwashyna TJ et al (2016) Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315(8):762–774. (PMID: 10.1001/jama.2016.0288269033355433435)
Singer M, Deutschman CS, Seymour CW et al (2016) The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315(8):801–810. (PMID: 10.1001/jama.2016.0287269033384968574)
Kyriazis I, Panagopoulos V, Kallidonis P et al (2015) Complications in percutaneous nephrolithotomy. World J Urol 33(8):1069–1077. (PMID: 10.1007/s00345-014-1400-825218854)
Zhong W, Leto G, Wang L, Zeng G (2015) Systemic inflammatory response syndrome after flexible ureteroscopic lithotripsy: a study of risk factors. J Endourol 29(1):25–28. (PMID: 10.1089/end.2014.040924999535)
Dybowski B, Bres-Niewada E, Rzeszutko M et al (2021) Risk factors for infectious complications after retrograde intrarenal surgery - a systematic review and narrative synthesis. Cent Eur J Urol 74(3):437–445.
Chan JY, Wong VK, Wong J et al (2021) Predictors of urosepsis in struvite stone patients after percutaneous nephrolithotomy. Invest Clin Urol 62(2):201–209. (PMID: 10.4111/icu.20200319)
Gao X, Lu C, Xie F et al (2020) Risk factors for sepsis in patients with struvite stones following percutaneous nephrolithotomy. World J Urol 38(1):219–229. (PMID: 10.1007/s00345-019-02748-030972490)
Gault MH, Longerich LL, Crane G et al (1995) Bacteriology of urinary tract stones. J Urol 153(4):1164–1170. (PMID: 10.1016/S0022-5347(01)67539-67869488)
Flannigan RK, Battison A, De S et al (2018) Evaluating factors that dictate struvite stone composition: a multi-institutional clinical experience from the EDGE research consortium. Can Urol Assoc J 12(4):131–136. (PMID: 10.5489/cuaj.480429319486)
Halinski A, Bhatti KH, Boeri L et al (2022) Spectrum of bacterial pathogens from urinary infections associated with struvite and metabolic stones. Diagnostics (Basel Switzerland) 13(1).
Cui H (2021) Distribution and drug resistance of pathogens causing urinary tract infection in patients with urinary calculi. Am J Translational Res 13(9):10554–10561.
De Lorenzis E, Alba AB, Cepeda M et al (2020) Bacterial spectrum and antibiotic resistance of urinary tract infections in patients treated for upper urinary tract calculi: a multicenter analysis. Eur J Clin Microbiol Infect Diseases: Official Publication Eur Soc Clin Microbiol 39(10):1971–1981. (PMID: 10.1007/s10096-020-03947-z)
Rivera M, Viers B, Cockerill P et al (2016) Pre- and postoperative predictors of infection-related complications in patients undergoing percutaneous nephrolithotomy. J Endourol 30(9):982–986. (PMID: 10.1089/end.2016.019127393153)
Lojanapiwat B, Kitirattrakarn P (2011) Role of preoperative and intraoperative factors in mediating infection complication following percutaneous nephrolithotomy. Urol Int 86(4):448–452. (PMID: 10.1159/00032410621508617)
Liu J, Zhou C, Gao W et al (2020) Does preoperative urine culture still play a role in predicting post-PCNL SIRS? A retrospective cohort study. Urolithiasis 48(3):251–256. (PMID: 10.1007/s00240-019-01148-831324955)
El-Nahas AR, Nabeeh MA, Laymon M et al (2021) Preoperative risk factors for complications of percutaneous nephrolithotomy. Urolithiasis 49(2):153–160. (PMID: 10.1007/s00240-020-01203-932740673)
Mariappan P, Smith G, Bariol SV et al (2005) Stone and pelvic urine culture and sensitivity are better than bladder urine as predictors of urosepsis following percutaneous nephrolithotomy: a prospective clinical study. J Urol 173(5):1610–1614. (PMID: 10.1097/01.ju.0000154350.78826.9615821509)
Fowler AJ, Ahmad T, Phull MK (2015) Meta-analysis of the association between preoperative anaemia and mortality after surgery. Br J Surg 102(11), 1314–1324.
Musallam KM, Tamim HM, Richards T et al (2011) Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet 378(9800):1396–1407. (PMID: 10.1016/S0140-6736(11)61381-021982521)
de Valente L, Hoffmann A, Weiss G (2021) Impact of bacterial infections on erythropoiesis. Expert Rev Anti Infect Ther 19(5):619–633. (PMID: 10.1080/14787210.2021.1841636)
معلومات مُعتمدة: RDY 2021-21 Peking University People's Hospital; RDE2023-11 Peking University People's Hospital; BHTPP2022082 Beijing Health Technologies Promotion Program
فهرسة مساهمة: Keywords: Complication; Flexible ureteroscopy; Percutaneous nephrolithotomy; Struvite stone; Urinary calculi
المشرفين على المادة: AW3EJL1462 (Struvite)
تواريخ الأحداث: Date Created: 20240902 Date Completed: 20240902 Latest Revision: 20240902
رمز التحديث: 20240903
DOI: 10.1007/s00345-024-05206-8
PMID: 39222253
قاعدة البيانات: MEDLINE
الوصف
تدمد:1433-8726
DOI:10.1007/s00345-024-05206-8