دورية أكاديمية
[Fibrous dysplasia].
| العنوان: | [Fibrous dysplasia]. |
|---|---|
| عنوان ترانسليتريتد: | Fibröse Dysplasie. |
| المؤلفون: | Waltermann A; Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland., Westhoff B; Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland. Westhoff@med.uni-duesseldorf.de. |
| المصدر: | Orthopadie (Heidelberg, Germany) [Orthopadie (Heidelb)] 2024 Oct; Vol. 53 (10), pp. 805-816. Date of Electronic Publication: 2024 Sep 05. |
| نوع المنشور: | Journal Article; English Abstract; Review |
| اللغة: | German |
| بيانات الدورية: | Publisher: Springer Medizin Country of Publication: Germany NLM ID: 9918384887206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-7153 (Electronic) Linking ISSN: 27317145 NLM ISO Abbreviation: Orthopadie (Heidelb) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Heidelberg, Germany] : Springer Medizin, [2022]- |
| مواضيع طبية MeSH: | Fibrous Dysplasia of Bone*/diagnosis , Fibrous Dysplasia of Bone*/pathology, Humans ; Fibrous Dysplasia, Polyostotic/pathology ; Fibrous Dysplasia, Polyostotic/diagnosis ; Fibrous Dysplasia, Polyostotic/therapy |
| مستخلص: | Fibrous dysplasia is a sporadically occurring benign skeletal disease characterized by the replacement of normal bone tissue with excessively proliferating cellular fibrous tissue. It can occur in a monostotic or polyostotic form. Depending on the location, number and size of the lesions, the clinical picture can vary from an asymptomatic disease to a severe disability. Typical problems are bone pain, bone deformities and pathological fractures. In combination with endocrinopathies and/or skin manifestations (café au lait spots), it is referred to as the McCune-Albright syndrome. The diagnosis is mainly carried out radiologically and the bony lesions are characterized by a cloudy, frosted glass-like aspect. Causal treatment is not possible. Orthopedic treatment includes pain relief, bone stabilization, deformity correction and, if necessary, lesion cleansing as well as the prevention of progression by means of antiresorptive medication. Pathological fractures are preferably stabilized with intramedullary osteosynthesis procedures. (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.) |
| References: | Feller L et al (2009) The nature of fibrous dysplasia. Head Face Med 5:22. (PMID: 10.1186/1746-160X-5-22198957122779176) Chapurlat RD, Orcel P (2008) Fibrous dysplasia of bone and McCune-Albright syndrome. Best Pract Res Clin Rheumatol 22(1):55–69. (PMID: 10.1016/j.berh.2007.11.00418328981) Benhamou J et al (2016) Prognostic Factors From an Epidemiologic Evaluation of Fibrous Dysplasia of Bone in a Modern Cohort: The FRANCEDYS Study. J Bone Miner Res 31(12):2167–2172. (PMID: 10.1002/jbmr.289427340799) Fitzpatrick KA et al (2004) Imaging findings of fibrous dysplasia with histopathologic and intraoperative correlation. AJR Am J Roentgenol 182(6):1389–1398. (PMID: 10.2214/ajr.182.6.182138915149980) Leet AI, Collins MT (2007) Current approach to fibrous dysplasia of bone and McCune-Albright syndrome. J Child Orthop 1(1):3–17. (PMID: 10.1007/s11832-007-0006-8193085002656698) Riddle ND, Bui MM (2013) Fibrous dysplasia. Arch Pathol Lab Med 137(1):134–138. (PMID: 10.5858/arpa.2012.0013-RS23276185) Collins MT, Singer FR, Eugster E (2012) McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia. Orphanet J Rare Dis 7(Suppl 1):S4 (Suppl 1). (PMID: 10.1186/1750-1172-7-S1-S4226409713359955) Wirth T (2020) Fibrous dysplasia. Orthopade 49(10):929–940. (PMID: 10.1007/s00132-020-03984-832960303) Javaid MK et al (2019) Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium. Orphanet J Rare Dis 14(1):139. (PMID: 10.1186/s13023-019-1102-9311961036567644) Hart ES et al (2007) Onset, progression, and plateau of skeletal lesions in fibrous dysplasia and the relationship to functional outcome. J Bone Miner Res 22(9):1468–1474. (PMID: 10.1359/jbmr.07051117501668) Kelly MH, Brillante B, Collins MT (2008) Pain in fibrous dysplasia of bone: age-related changes and the anatomical distribution of skeletal lesions. Osteoporos Int 19(1):57–63. (PMID: 10.1007/s00198-007-0425-x17622477) Ippolito E et al (2003) Natural history and treatment of fibrous dysplasia of bone: a multicenter clinicopathologic study promoted by the European Pediatric Orthopaedic Society. J Pediatr Orthop B 12(3):155–177. (PMID: 12703030) Leet AI et al (2004) Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome. J Bone Miner Res 19(4):571–577. (PMID: 10.1359/JBMR.030126215005844) Rödl R, Götze C (2008) Fibrous dysplasia. Orthopade 37(1):49–55. (PMID: 10.1007/s00132-007-1180-618084739) Ippolito E et al (2014) Radiographic classification of coronal plane femoral deformities in polyostotic fibrous dysplasia. Clin Orthop Relat Res 472(5):1558–1567. (PMID: 10.1007/s11999-013-3380-124249535) Gorgolini G et al (2022) Surgical correction of valgus deformities of the knee in Polyostotic Fibrous Dysplasia. Orthop Rev (Pavia) 14(5):38827. (PMID: 10.52965/001c.3882736540073) Mancini F et al (2009) Scoliosis and spine involvement in fibrous dysplasia of bone. Eur Spine J 18(2):196–202. (PMID: 10.1007/s00586-008-0860-1191300982899336) Leet AI et al (2004) Fibrous dysplasia in the spine: prevalence of lesions and association with scoliosis. J Bone Joint Surg Am 86(3):531–537. (PMID: 10.2106/00004623-200403000-0001114996879) Kuznetsov SA et al (2008) Age-dependent demise of GNAS-mutated skeletal stem cells and “normalization” of fibrous dysplasia of bone. J Bone Miner Res 23(11):1731–1740. (PMID: 10.1359/jbmr.080609185976242585500) Ruggieri P et al (1994) Malignancies in fibrous dysplasia. Cancer 73(5):1411–1424. (PMID: 10.1002/1097-0142(19940301)73:5<1411::AID-CNCR2820730516>3.0.CO;2-T8111708) Hefti F (2013) Kinderorthopädie in der Praxis. Heidelberg Springer Berlin, Heidelberg. Kinnunen AR, Sironen R, Sipola P (2020) Magnetic resonance imaging characteristics in patients with histopathologically proven fibrous dysplasia—a systematic review. Skelet Radiol 49(6):837–845. (PMID: 10.1007/s00256-020-03388-x) de Castro LF et al (2023) Safety and Efficacy of Denosumab for Fibrous Dysplasia of Bone. N Engl J Med 388(8):766–768. (PMID: 10.1056/NEJMc22148623681244110015375) Lindner N et al (2000) Surgical reconstruction of fibrous dysplasia of bone in long-term follow-up. Z Orthop Ihre Grenzgeb 138(2):152–158. (PMID: 10.1055/s-2000-1013110820882) Gorgolini G et al (2022) Surgical treatment of femoral deformities in polyostotic fibrous dysplasia and McCune-Albright syndrome: A literature review. World J Orthop 13(3):329–338. (PMID: 10.5312/wjo.v13.i3.329353172518935334) Hefti F, Donnan L, Krieg AH (2017) Treatment of shepherd’s crook deformity in patients with polyostotic fibrous dysplasia using a new type of custom made retrograde intramedullary nail: a technical note. J Child Orthop 11(1):64–70. (PMID: 10.1302/1863-2548.11.170002284393115382339) Popkov A et al (2020) Lower limb lengthening and deformity correction in polyostotic fibrous dysplasia using external fixation and flexible intramedullary nailing. J Orthop 21:192–198. (PMID: 10.1016/j.jor.2020.03.014322560037125318) Berglund JA et al (2018) Scoliosis in Fibrous Dysplasia/McCune-Albright Syndrome: Factors Associated With Curve Progression and Effects of Bisphosphonates. J Bone Miner Res 33(9):1641–1648. (PMID: 10.1002/jbmr.344629669167) Guille JT, Kumar SJ, MacEwen GD (1998) Fibrous dysplasia of the proximal part of the femur. Long-term results of curettage and bone-grafting and mechanical realignment. J Bone Joint Surg Am 80(5):648–658. (PMID: 10.2106/00004623-199805000-000059611025) |
| فهرسة مساهمة: | Keywords: Benign bone tumor; Bone deformities; McCune-Albright syndrome; Pathological fracture; Skeletal disease Local Abstract: [Publisher, German] Die fibröse Dysplasie ist eine sporadisch auftretende, gutartige Skeletterkrankung, die durch den Ersatz normalen Knochengewebes durch exzessiv proliferierendes, zellulär fibröses Gewebe charakterisiert ist. Sie kann monostotisch oder polyostotisch auftreten. Je nach Lokalisation, Anzahl und Größe der Herde kann das klinische Bild von einer asymptomatischen Erkrankung bis zu einer ausgeprägten Behinderung variieren. Typische Probleme sind Knochenschmerzen, knöcherne Deformierungen sowie pathologische Frakturen. In Kombination mit Endokrinopathien und/oder Hautveränderungen (Café-au-lait-Flecken) spricht man von einem McCune-Albright-Syndrom. Die Diagnose erfolgt überwiegend radiologisch, die knöchernen Läsionen sind charakterisiert durch einen trüben, milchglasartigen Aspekt. Eine kausale Therapie ist nicht möglich. Die orthopädische Therapie umfasst die Schmerzlinderung, die Knochenstabilisierung, Deformitätenkorrektur und ggf. Herdsanierung sowie die Vermeidung der Progredienz mittels antiresorptiver Medikamente. Pathologische Frakturen werden bevorzugt mit intramedullären Osteosyntheseverfahren stabilisiert. |
| تواريخ الأحداث: | Date Created: 20240905 Date Completed: 20240926 Latest Revision: 20240926 |
| رمز التحديث: | 20240926 |
| DOI: | 10.1007/s00132-024-04548-w |
| PMID: | 39235640 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. | تدمد: | 2731-7153 |
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| DOI: | 10.1007/s00132-024-04548-w |