دورية أكاديمية
أعرض في EDS

Heterotopic ossification Post-Guillain-Barre syndrome in Saudi Arabia: a case report.

التفاصيل البيبلوغرافية
العنوان: Heterotopic ossification Post-Guillain-Barre syndrome in Saudi Arabia: a case report.
المؤلفون: Aldhilan MM; Department of Orthopedic Surgery, Ar Rass General Hospital, Ar Rass., Alshahrani AH; Department of Orthopedic Surgery, College of Medicine, Qassim University, Buraydah, Saudi Arabia.
المصدر: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Jun 26; Vol. 86 (9), pp. 5509-5512. Date of Electronic Publication: 2024 Jun 26 (Print Publication: 2024).
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Country of Publication: England NLM ID: 101616869 Publication Model: eCollection Cited Medium: Print ISSN: 2049-0801 (Print) Linking ISSN: 20490801 NLM ISO Abbreviation: Ann Med Surg (Lond) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2023- : [London] : Wolters Kluwer
Original Publication: London : Surgical Associates Ltd., 2012-
مستخلص: Background: Heterotopic ossification (HO) is the formation of bone within the soft tissues. It can be a complication of Guillain-Barre syndrome (GBS). There are many risk factors for HO, including male sex, mechanical ventilation, and neurogenic trauma. Myelin and axons are the main targets and areas of injury in GBS, an autoimmune-inflammatory neuropathy. Literature shows that this may possibly be associated with the initial administration of the COVID-19 vaccine and GBS.
Presentation of the Case: A 27-year-old male was diagnosed with bile reflux gastritis. Days later, he presented to the emergency room (ER) with progressive weakness and a critical condition that required ICU. The patient undergoes intubation and remains in the ICU for 4 months. The patient, after extensive rehabilitation, started to complain of left hip pain and limitations of motion. Radiographs confirmed the HO diagnosis. Past drug history showed patients received a single dose of the COVID-19 vaccine 15 days before presentation to the ER.
Discussion: There is no clear association between the COVID-19 vaccination and GBS. HO is the formation of abnormal bone within soft tissue. HO post-GBS usually affects large joints like the hips, knees, and shoulders. Researchers poorly understand the pathogenesis of GBS.
Conclusion: Despite the absence of a definitive correlation between GSB and the COVID-19 vaccine. Physicians should maintain a state of suspicion while treating patients with a progressive weakness. Additional research is required.
Competing Interests: The authors declare that they have no conflicts of interests.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.
(Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
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فهرسة مساهمة: Keywords: COVID-19; Guillain–Barré syndrome; arthroplasty; case report; heterotopic ossification
تواريخ الأحداث: Date Created: 20240906 Latest Revision: 20240910
رمز التحديث: 20240910
مُعرف محوري في PubMed: PMC11374238
DOI: 10.1097/MS9.0000000000002312
PMID: 39238987
قاعدة البيانات: MEDLINE
الوصف
تدمد:2049-0801
DOI:10.1097/MS9.0000000000002312