دورية أكاديمية
Low-Mineral Water Diminishes the Bone Benefits of Boron.
| العنوان: | Low-Mineral Water Diminishes the Bone Benefits of Boron. |
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| المؤلفون: | Huang T; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Hao Y; State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Tan Y; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Dai Q; Department of Orthopedics, Southwest Hospital, Army Medical University, Chongqing 400038, China., Chen W; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Cui K; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Luo J; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Zeng H; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Shu W; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China., Huang Y; Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University, Chongqing 400038, China. |
| المصدر: | Nutrients [Nutrients] 2024 Aug 28; Vol. 16 (17). Date of Electronic Publication: 2024 Aug 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI Publishing |
| مواضيع طبية MeSH: | Boron*/pharmacology , Mice, Inbred BALB C* , Mineral Waters* , Seawater*/chemistry , Bone and Bones*/drug effects , Bone and Bones*/metabolism, Animals ; Male ; Mice ; Bone Density/drug effects ; Drinking Water ; Biomarkers/blood ; Lumbar Vertebrae/drug effects ; Femur/drug effects |
| مستخلص: | This study looked at how desalinated seawater, which has low minerals and high boron, could affect bone health. Prior research suggests that low mineral water may harm bone health and boron could be beneficial, but the overall impact on bone health is still unclear. Eighty-nine-week-old male Balb/C mice were allocated into eight groups and administered either tap water or purified water with varying boron concentrations (0, 5, 40, and 200 mg/L). They were kept in an environment mimicking tropical conditions (35-40 °C, 70-80% humidity) and underwent daily treadmill exercise for 13 weeks. At the 14th week, serum, femora, and lumbar vertebrae were collected for mineral metabolism, bone biomarker, microstructure, and biomechanics evaluation. Boron exposure improved bone formation, microstructure, and biomechanics initially but the benefits weakened with higher levels of exposure ( p < 0.05). Co-exposure to purified water elevated serum boron but weakened the promotion of boron on bone minerals and the bone benefits of boron compared to tap water ( p < 0.05). Thus, when studying the health effects of boron in desalinated seawater, it is crucial to look at various health effects beyond bone health. Furthermore, it is important to consider the mineral composition of drinking water when using boron for bone health benefits. |
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| معلومات مُعتمدة: | National Key R&D Program of China (Key Special Project for Marine Environmental Security and Sustainable Development of Coral Reefs 2021-01) National Science and Technology Council |
| فهرسة مساهمة: | Keywords: bone biomechanics; bone microstructure; boron; desalinated seawater; low mineral water; mineral metabolism |
| المشرفين على المادة: | N9E3X5056Q (Boron) 0 (Mineral Waters) 0 (Drinking Water) 0 (Biomarkers) |
| تواريخ الأحداث: | Date Created: 20240914 Date Completed: 20240914 Latest Revision: 20240916 |
| رمز التحديث: | 20240916 |
| مُعرف محوري في PubMed: | PMC11397211 |
| DOI: | 10.3390/nu16172881 |
| PMID: | 39275197 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2072-6643 |
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| DOI: | 10.3390/nu16172881 |