دورية أكاديمية

Comprehensive analysis of risk factors for postoperative wound infection following open reduction and internal fixation of Rib fractures.

التفاصيل البيبلوغرافية
العنوان: Comprehensive analysis of risk factors for postoperative wound infection following open reduction and internal fixation of Rib fractures.
المؤلفون: Li H; Cardio-Thoracic Surgery Department, Qionghai People's Hospital, Qionghai City, 571400, Hainan Province, China., Zheng X; Cardio-Thoracic Surgery Department, Qionghai People's Hospital, Qionghai City, 571400, Hainan Province, China., Gao J; Gynecology-Breast And Thyroid Surgery Department, Qionghai People's Hospital, No. 33 Fuhai Road, Jiaji Town, Qionghai City, 571400, Hainan Province, China. gj605758303@outlook.com.
المصدر: BMC infectious diseases [BMC Infect Dis] 2024 Sep 19; Vol. 24 (1), pp. 1013. Date of Electronic Publication: 2024 Sep 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Surgical Wound Infection*/epidemiology , Surgical Wound Infection*/etiology , Fracture Fixation, Internal*/adverse effects , Rib Fractures*/surgery, Humans ; Male ; Risk Factors ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Adult ; Open Fracture Reduction/adverse effects ; Operative Time ; Length of Stay/statistics & numerical data
مستخلص: Background: Postoperative wound infections (PWIs) significantly impact patient outcomes following open reduction and internal fixation (ORIF) of rib fractures. Identifying and understanding risk factors associated with these infections are crucial for improving surgical outcomes and patient care.
Methods: This retrospective study, conducted from January 2020 to October 2023 at our institution, aimed to analyze the risk factors for PWIs in patients undergoing ORIF for rib fractures. A total of 150 patients were included, with 50 in the infected group and 100 in the non-infected control group, matched for demographic and clinical characteristics. Data on variables such as intraoperative blood loss, hospital stay duration, body mass index (BMI), operation time, presence of anemia, drainage time, diabetes mellitus status, smoking habits, and age were collected. Statistical analysis involved univariate and multivariate logistic regression using SPSS software (Version 27.0), with p-values < 0.05 considered statistically significant.
Results: Univariate analysis revealed no significant association between intraoperative blood loss or hospital stay duration and PWIs. However, operation time ≥ 5 h, anemia, drainage time ≥ 7 days, diabetes mellitus, smoking, and age ≥ 60 years were significantly associated with higher PWI rates. Multivariate logistic regression confirmed these factors as independent predictors of PWIs, with operation time and diabetes mellitus showing particularly strong associations.
Conclusions: Prolonged operation time, anemia, extended drainage, diabetes mellitus, smoking, and advanced age significantly increase the risk of PWIs following ORIF for rib fractures. Early identification and targeted management of these risk factors are essential to reduce the incidence of infections and improve postoperative outcomes.
(© 2024. The Author(s).)
References: Curr Diab Rep. 2017 Feb;17(2):13. (PMID: 28265893)
Cureus. 2022 Nov 25;14(11):e31890. (PMID: 36579237)
Surg Infect (Larchmt). 2006;7 Suppl 1:S7-11. (PMID: 16834549)
Anaesthesiol Intensive Ther. 2021;53(1):25-29. (PMID: 33586421)
JAMA Surg. 2017 May 1;152(5):484. (PMID: 28199452)
J Trauma Acute Care Surg. 2017 Mar;82(3):618-626. (PMID: 28030502)
Medicine (Baltimore). 2022 Dec 30;101(52):e32429. (PMID: 36596026)
Infect Control Hosp Epidemiol. 2016 Jan;37(1):88-99. (PMID: 26503187)
Am J Surg. 2016 Apr;211(4):761-7. (PMID: 26899958)
Surg Infect (Larchmt). 2017 Aug/Sep;18(6):722-735. (PMID: 28832271)
Cureus. 2022 May 19;14(5):e25138. (PMID: 35747035)
J Trauma Acute Care Surg. 2020 Aug;89(2):411-418. (PMID: 32282759)
Eur Rev Med Pharmacol Sci. 2019 Apr;23(2 Suppl):224-239. (PMID: 30977890)
World J Surg. 2018 Dec;42(12):3888-3896. (PMID: 29978247)
Transfusion. 2009 Sep;49(9):1964-70. (PMID: 19453989)
Surg Infect (Larchmt). 2021 Mar;22(2):168-173. (PMID: 32397903)
Surg Today. 2021 Feb;51(2):212-218. (PMID: 32892295)
Surg Infect (Larchmt). 2017 Feb/Mar;18(2):206-214. (PMID: 28004986)
Surg Infect (Larchmt). 2017 May/Jun;18(4):440-446. (PMID: 28402740)
Trials. 2020 Feb 28;21(1):234. (PMID: 32111244)
Exp Ther Med. 2018 Dec;16(6):4650-4654. (PMID: 30542416)
J Surg Res. 2018 Sep;229:134-144. (PMID: 29936980)
فهرسة مساهمة: Keywords: Open reduction and internal fixation; Postoperative wound infections; Rib fractures; Risk factors
تواريخ الأحداث: Date Created: 20240919 Date Completed: 20240919 Latest Revision: 20240922
رمز التحديث: 20240922
مُعرف محوري في PubMed: PMC11414111
DOI: 10.1186/s12879-024-09946-1
PMID: 39300348
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2334
DOI:10.1186/s12879-024-09946-1