دورية أكاديمية
A Comparison of Commonly Utilized Diagnostic Biopsy Techniques for Pediatric Patients With Cancer: A Systematic Review by the APSA Cancer Committee.
| العنوان: | A Comparison of Commonly Utilized Diagnostic Biopsy Techniques for Pediatric Patients With Cancer: A Systematic Review by the APSA Cancer Committee. |
|---|---|
| المؤلفون: | Teke M; Department of Surgery, University of Texas at Southwestern Medical Center, Dallas, TX, USA., Rich BS; Division of Pediatric Surgery, Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY, USA., Walther A; Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Schwartz D; Division of Pediatric Surgery, Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA., McDuffie LA; Division of Pediatric General and Thoracic Surgery, Doernbecher Children's Hospital, Oregon Health and Science University, Portland, OR, USA., Butera G; National Institutes of Health Library, Office of Research Services, U.S. Department of Health and Human Services, Bethesda, MD, USA., Roach JP; Division of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA., Rothstein DH; Dept of General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA, USA., Lal DR; Division of Pediatric Surgery, Medical College of Wisconsin, Children's Wisconsin, Milwaukee, WI, USA., Riehle K; Dept of General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA, USA., Espinoza A; Divisions of Pediatric Surgery and Surgical Research, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA., Cost N; Division of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA., Tracy E; Division of Pediatric Surgery, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Rodeberg D; Division of Pediatric Surgery, Kentucky Children's Hospital, Department of Surgery, University of Kentucky College of Medicine, Lexington KY, USA., Lautz T; Division of Pediatric Surgery, Ann & Robert H Lurie Children's Hospital of Chicago, Northwestern University, Chicago, IL, USA., Aldrink JH; Division of Pediatric Surgery, Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA., Brown EG; Division of Pediatric Surgery, Department of Surgery, University of California Davis Children's Hospital, Sacramento, CA, USA. Electronic address: egbrown@ucdavis.edu. |
| المصدر: | Journal of pediatric surgery [J Pediatr Surg] 2024 Sep 02, pp. 161893. Date of Electronic Publication: 2024 Sep 02. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Saunders Country of Publication: United States NLM ID: 0052631 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-5037 (Electronic) Linking ISSN: 00223468 NLM ISO Abbreviation: J Pediatr Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : Saunders Original Publication: New York. |
| مستخلص: | Background: Historically, surgical biopsy (SB) for diagnosis of pediatric solid tumors was considered necessary to provide adequate tissue for histologic and molecular analysis. Less invasive biopsy techniques such as image-guided core needle biopsy (CNB), have shown comparable accuracy with decreased morbidity in some adult studies. However, data regarding the safety and efficacy of CNB in pediatric tumors is limited. This study's aim was to assess the overall rate of successful diagnosis and safety of CNB compared to SB in children with malignancies. Methods: A PRISMA compliant systematic review was performed in MEDLINE via PubMed, Embase and CINAHL Plus database searches from 2010 to 2023. Studies were included with relevance to the following clinical question: For children with concern for malignancy requiring biopsy for diagnosis, how does CNB compare to open or laparoscopic/thoracoscopic SB in terms of safety and diagnostic efficacy? Data for patients ≤21 years requiring biopsy for diagnosis of liver tumors, neuroblastoma (NB), soft tissue sarcoma (STS), and lymphoma were included. Results: Twenty-seven studies including 2477 patients met inclusion criteria, with 2065 undergoing CNB and 412 SB. Of the 2477 patients, 820 patients had NB, 307 liver tumors, 96 STS, 151 lymphoma, and 1103 patients were from studies that included multiple diagnoses. The average complication rate for CNB was 2.9% compared to 21.4% for SB (p < 0.001). Bleeding was the most common complication in both groups, but significantly higher after SB (22.1% vs 2.3%) (p < 0.001). CNB was diagnostic in 90.8% of patients compared to 98.8% who underwent SB (p < 0.001). Conclusions: Rates of successful diagnosis were greater than 90% for both CNB and SB, though significantly higher for SB. Conversely, complication rates were close to ten times higher after SB compared to CNB. Given its relatively lower risk profile, CNB can be a safe and useful diagnostic tool for children with solid malignancies. Research focused on enhancing CNB's diagnostic accuracy while maintaining low morbidity should be further explored. Level of Evidence: Treatment study, Level III. Competing Interests: Declaration of competing interest The authors have nothing to declare. (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Children with cancer; Core needle biopsy; Diagnostic techniques; Pediatric cancer; Pediatric malignancies; Surgical biopsy |
| تواريخ الأحداث: | Date Created: 20240924 Latest Revision: 20240924 |
| رمز التحديث: | 20240925 |
| DOI: | 10.1016/j.jpedsurg.2024.161893 |
| PMID: | 39317569 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1531-5037 |
|---|---|
| DOI: | 10.1016/j.jpedsurg.2024.161893 |