دورية أكاديمية
Clinical study of a new antikeloid agent.
العنوان: | Clinical study of a new antikeloid agent. |
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المؤلفون: | Bossé JP, Papillon J, Frenette G, Dansereau J, Cadotte M, Le Lorier J |
المصدر: | Annals of plastic surgery [Ann Plast Surg] 1979 Jul; Vol. 3 (1), pp. 13-21. |
نوع المنشور: | Clinical Trial; Controlled Clinical Trial; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Little, Brown And Company Country of Publication: United States NLM ID: 7805336 Publication Model: Print Cited Medium: Print ISSN: 0148-7043 (Print) Linking ISSN: 01487043 NLM ISO Abbreviation: Ann Plast Surg Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Boston Ma : Little, Brown And Company Original Publication: Boston, Little, Brown. |
مواضيع طبية MeSH: | Glycosides/*therapeutic use , Keloid/*drug therapy , Triterpenes/*therapeutic use, Adult ; Burns/complications ; Clinical Trials as Topic ; Double-Blind Method ; Humans ; Placebos ; Plant Extracts/therapeutic use ; Time Factors ; Wound Healing |
مستخلص: | An old healing drug has been assessed and found to be of clinical value in stopping the inflammatory phase of hypertrophic scars and keloids. So far, this drug has no known side effects other than occasional mild gastric intolerance and allergic reaction. Our findings are well supported in the literature. The effect of the drug on other forms of connective tissue anomalies that present an inflammatory phase is similar to that on keloids, gradually brining scars to the maturation phase. Our results on this will be published later. Madecassol has also been shown to have a preventive effect on burn and postoperative hypertrophic scars. It compares favorably in effectiveness with compression bandaging, and gives more lasting results than intralesional cortisone or radiation therapy. Finally, Madecassol has a placebo effect of 29%-well within acceptable limits. |
المشرفين على المادة: | 0 (Glycosides) 0 (Placebos) 0 (Plant Extracts) 0 (Triterpenes) PKO39VY215 (asiaticoside) |
تواريخ الأحداث: | Date Created: 19790701 Date Completed: 19800625 Latest Revision: 20151119 |
رمز التحديث: | 20221208 |
PMID: | 396846 |
قاعدة البيانات: | MEDLINE |
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