دورية أكاديمية

A simple mathematical method revealing the early stage of acute leukemia in patients with cytopenias.

التفاصيل البيبلوغرافية
العنوان: A simple mathematical method revealing the early stage of acute leukemia in patients with cytopenias.
المؤلفون: Jaworkowsky LI, Solovey DY, Rhausova LY, Udris OY, Kelman IA, Libenson MN, Ivanowa LW
المصدر: Folia haematologica (Leipzig, Germany : 1928) [Folia Haematol Int Mag Klin Morphol Blutforsch] 1984; Vol. 111 (5), pp. 701-6.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Akademische Verlagsgesellschaft M.B.H Country of Publication: Germany NLM ID: 0374615 Publication Model: Print Cited Medium: Print ISSN: 0323-4347 (Print) Linking ISSN: 03234347 NLM ISO Abbreviation: Folia Haematol Int Mag Klin Morphol Blutforsch Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Leipzig : Akademische Verlagsgesellschaft M.B.H.
مواضيع طبية MeSH: Anemia, Aplastic/*blood , Leukemia/*blood , Pancytopenia/*blood , Preleukemia/*blood, Acute Disease ; Anemia, Aplastic/diagnosis ; Bone Marrow Cells ; Diagnosis, Differential ; Humans ; Leukemia/diagnosis ; Leukocyte Count ; Pancytopenia/diagnosis ; Preleukemia/diagnosis
مستخلص: On the basis of findings in examinations made in 50 patients (25 with hypoplastic anaemia and 15 in the hypoplastic stage of acute leukemia) a simple mathematical method was developed for the differential diagnosis of these two diseases. The following laboratory findings were used for calculating a formula: cellularity of the bone-marrow, percentage of blast cells in the myelogram, percentage of blast cells in leukocyte concentrate, morphology of erythrocytes, presence of normoblastosis, percentage of monocytes and absolute number of neutrophils in the peripheral blood. This method allows the correct diagnosis to be made in 91% of cases with hypoplastic anaemia and in 100% of cases with acute leukemia. By using 7 laboratory findings to be obtained easily this method will enable a correct diagnosis to be made even in those situations where hitherto it was very difficult to make a differential diagnosis or where it was impossible at all.
تواريخ الأحداث: Date Created: 19840101 Date Completed: 19850227 Latest Revision: 20041117
رمز التحديث: 20231215
PMID: 6083946
قاعدة البيانات: MEDLINE