دورية أكاديمية
A randomised trial of strategies to improve patient compliance with anticonvulsant therapy.
| العنوان: | A randomised trial of strategies to improve patient compliance with anticonvulsant therapy. |
|---|---|
| المؤلفون: | Peterson GM, McLean S, Millingen KS |
| المصدر: | Epilepsia [Epilepsia] 1984 Aug; Vol. 25 (4), pp. 412-7. |
| نوع المنشور: | Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print Cited Medium: Print ISSN: 0013-9580 (Print) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Malden, MA : Blackwell Science Original Publication: Copenhagen : Munskgaard |
| مواضيع طبية MeSH: | Patient Compliance*, Anticonvulsants/*therapeutic use, Adolescent ; Adult ; Anticonvulsants/blood ; Carbamazepine/blood ; Carbamazepine/therapeutic use ; Clinical Trials as Topic ; Counseling ; Drug Packaging ; Epilepsy/drug therapy ; Female ; Humans ; Male ; Phenytoin/blood ; Phenytoin/therapeutic use ; Random Allocation ; Valproic Acid/blood ; Valproic Acid/therapeutic use |
| مستخلص: | Fifty-three hospital outpatients with epilepsy were randomly allocated to either a control or an intervention group. Patients in the intervention group were subjected to a combination of compliance-improving strategies: patient counselling, a special medication container, self-recording of medication intake and seizures, and mailed reminders to collect prescription refills and attend clinic appointments. Compliance with anticonvulsant therapy (as measured by plasma anticonvulsant levels and prescription refill frequencies), and seizure frequency, were evaluated in each patient prior to intervention and 6 months afterwards. Patient compliance and clinical control improved significantly in the intervention group patients. Seizure frequency was, on average, halved following intervention. Compliance and seizure frequency were unaltered in the control group. Intervention failed to improve clinic appointment keeping. Poor compliance with drug therapy commonly confounds the treatment of epilepsy. This study shows that compliance can be improved and seizure frequency lessened by strategies that are easily incorporated into the routine management of epileptic patients. |
| المشرفين على المادة: | 0 (Anticonvulsants) 33CM23913M (Carbamazepine) 614OI1Z5WI (Valproic Acid) 6158TKW0C5 (Phenytoin) |
| تواريخ الأحداث: | Date Created: 19840801 Date Completed: 19840910 Latest Revision: 20190813 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1111/j.1528-1157.1984.tb03436.x |
| PMID: | 6430689 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!