دورية أكاديمية
[Injectable contraceptive, DMPA, serum HDL cholesterol and heart infarct].
العنوان: | [Injectable contraceptive, DMPA, serum HDL cholesterol and heart infarct]. |
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عنوان ترانسليتريتد: | Prikpil, serum-HDL-cholesterol en hartinfarct. |
المؤلفون: | Kremer J, de Bruijn HW, Hindriks FR |
المصدر: | Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 1981 Aug 25; Vol. 125 (35), pp. 1418-21. |
نوع المنشور: | Comparative Study; English Abstract; Journal Article |
اللغة: | Dutch; Flemish |
بيانات الدورية: | Publisher: Vereniging NTvG Country of Publication: Netherlands NLM ID: 0400770 Publication Model: Print Cited Medium: Print ISSN: 0028-2162 (Print) Linking ISSN: 00282162 NLM ISO Abbreviation: Ned Tijdschr Geneeskd Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2017?-: Amsterdam : Vereniging NTvG Original Publication: Houten : Bohn Stafleu van Loghum |
مواضيع طبية MeSH: | Cholesterol/*blood , Lipoproteins, HDL/*blood , Medroxyprogesterone/*analogs & derivatives, Adult ; Cholesterol, HDL ; Delayed-Action Preparations ; Female ; Humans ; Injections, Intramuscular ; Intrauterine Devices ; Medroxyprogesterone/administration & dosage ; Medroxyprogesterone/pharmacology ; Medroxyprogesterone Acetate ; Middle Aged ; Myocardial Infarction/chemically induced ; Risk |
فهرسة مساهمة: | Indexing Agency: PIP Local ID #: 005989. Indexing Agency: POP Local ID #: 00106371. Keywords: Biology; Cardiovascular Effects*; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Diseases; Family Planning; Heart Diseases*; Injectables*; Lipid Metabolic Effects--analysis*; Lipids; Medroxyprogesterone Acetate*; Physiology Note: TJ: NEDERLANDS TIJDSCHRIFT VOOR GENEESKUNDE. Local Abstract: [PIP] In 23 women who had used the injectable contraceptive depot medroxyprogesterone acetate (DMPA) for at least 1 year, the mean serum high-density lipoprotein cholesterol (HDL-C) level was distinctly lower than in 23 women carrying an IUD. The high serum DMPA levels during the 1st few weeks after a subsequent DMPA injection, and the low levels 12 weeks after the injection were found to be associated with the same (low) serum HDL-C level. For this reason, a fall in the serum HDL-C level in DMPA users is probably not a direct effect of the DMPA, but rather an indirect effect of the diminished production of endogenous estrogens in the ovaries of DMPA users. Though the investigation does not justify definite conclusions, it appears advisable not to prescribe DMPA to women with an increased risk of atherosclerosis and myocardial infarction. (author's) |
المشرفين على المادة: | 0 (Cholesterol, HDL) 0 (Delayed-Action Preparations) 0 (Lipoproteins, HDL) 97C5T2UQ7J (Cholesterol) C2QI4IOI2G (Medroxyprogesterone Acetate) HSU1C9YRES (Medroxyprogesterone) |
تواريخ الأحداث: | Date Created: 19810825 Date Completed: 19811122 Latest Revision: 20131121 |
رمز التحديث: | 20240627 |
PMID: | 6456421 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0028-2162 |
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