دورية أكاديمية
Dioxin in soil: bioavailability after ingestion by rats and guinea pigs.
| العنوان: | Dioxin in soil: bioavailability after ingestion by rats and guinea pigs. |
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| المؤلفون: | McConnell EE, Lucier GW, Rumbaugh RC, Albro PW, Harvan DJ, Hass JR, Harris MW |
| المصدر: | Science (New York, N.Y.) [Science] 1984 Mar 09; Vol. 223 (4640), pp. 1077-9. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: New York, N.Y. : [s.n.] 1880- |
| مواضيع طبية MeSH: | Soil Pollutants*/toxicity, Dioxins/*metabolism , Polychlorinated Dibenzodioxins/*metabolism, Animals ; Aryl Hydrocarbon Hydroxylases/biosynthesis ; Biological Availability ; Body Weight/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Eating ; Enzyme Induction ; Female ; Guinea Pigs ; Intestinal Absorption ; Liver/drug effects ; Male ; Microsomes, Liver/enzymology ; Organ Size/drug effects ; Polychlorinated Dibenzodioxins/toxicity ; Rats ; Rats, Inbred Strains ; Thymus Gland/drug effects |
| مستخلص: | Soil environmentally contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was given by gavage to guinea pigs and rats. The development of a characteristic clinicopathologic syndrome in guinea pigs, the induction of aryl hydrocarbon hydroxylase in rats, and the presence of TCDD in the livers of both species show that TCDD in soil exhibits high biological availability after ingestion. |
| المشرفين على المادة: | 0 (Dioxins) 0 (Polychlorinated Dibenzodioxins) 0 (Soil Pollutants) 9035-51-2 (Cytochrome P-450 Enzyme System) EC 1.14.14.1 (Aryl Hydrocarbon Hydroxylases) |
| تواريخ الأحداث: | Date Created: 19840309 Date Completed: 19840321 Latest Revision: 20190618 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1126/science.6695194 |
| PMID: | 6695194 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0036-8075 |
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| DOI: | 10.1126/science.6695194 |