دورية أكاديمية
A comparison of methods of lidocaine administration in patients.
| العنوان: | A comparison of methods of lidocaine administration in patients. |
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| المؤلفون: | Salzer LB, Weinrib AB, Marina RJ, Lima JJ |
| المصدر: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 1981 May; Vol. 29 (5), pp. 617-24. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print Cited Medium: Print ISSN: 0009-9236 (Print) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Hoboken, NJ : Wiley Original Publication: St. Louis : C.V. Mosby |
| مواضيع طبية MeSH: | Lidocaine/*administration & dosage, Aged ; Arrhythmias, Cardiac/drug therapy ; Computers ; Female ; Humans ; Infusions, Parenteral ; Injections, Intravenous ; Kinetics ; Lidocaine/blood ; Male ; Middle Aged ; Models, Biological |
| مستخلص: | A three-step method for administering lidocaine intravenously was developed and tested in 19 patients. Of all plasma concentrations measured, 70% were within the desired range of 2 to 4 micrograms/ml after the new method of lidocaine administration. Compared with other methods it is superior with respect to percent of time in the therapeutic range. No ventricular arrhythmias were evident, and no toxicities were associated with the new method. Infusions of lidocaine for more than 6 hr were associated with progressive increases in plasma concentrations that were higher (p less than 0.01) at 24 hr than at 6 hr. |
| المشرفين على المادة: | 98PI200987 (Lidocaine) |
| تواريخ الأحداث: | Date Created: 19810501 Date Completed: 19810623 Latest Revision: 20190512 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1038/clpt.1981.86 |
| PMID: | 7214792 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0009-9236 |
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| DOI: | 10.1038/clpt.1981.86 |