Inhibitory effect of growth hormone on Gross passage A virus-induced thymus leukemia in C3Hf mice.

التفاصيل البيبلوغرافية
العنوان:	Inhibitory effect of growth hormone on Gross passage A virus-induced thymus leukemia in C3Hf mice.
المؤلفون:	Duquesnoy RJ, Pedersen GM
المصدر:	Cancer research [Cancer Res] 1979 Feb; Vol. 39 (2 Pt 1), pp. 415-8.
نوع المنشور:	Journal Article; Research Support, U.S. Gov't, P.H.S.
اللغة:	English
بيانات الدورية:	Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print ISSN: 0008-5472 (Print) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
أسماء مطبوعة:	Publication: Baltimore, Md. : American Association for Cancer Research Original Publication: Chicago [etc.]
مواضيع طبية MeSH:	Growth Hormone/pharmacology , Leukemia, Experimental/prevention & control , Thymus Neoplasms/*prevention & control, AKR murine leukemia virus ; Animals ; Animals, Newborn ; Female ; Leukemia, Experimental/etiology ; Male ; Mice ; Mice, Inbred C3H ; Thymus Gland/drug effects ; Thymus Neoplasms/etiology ; Tumor Virus Infections/prevention & control
مستخلص:	Administration of ovine growth hormone to young C3Hf mice inhibited Gross passage A virus-induced leukemogenesis as manifested by a delayed onset and a lower incidence of thymus leukemia. These results can be interpreted that growth hormone inhibited thymus-dependent leukemogenesis perhaps through thymotrophic influences which prevented or delayed the thymus involution believed to be essential for leukemia change. In female but not in male Gross passage A virus-infected mice, development of a thymus-independent leukemia appeared to be promoted by growth hormone.
المشرفين على المادة:	9002-72-6 (Growth Hormone)
تواريخ الأحداث:	Date Created: 19790201 Date Completed: 19790425 Latest Revision: 20061115
رمز التحديث:	20221213
PMID:	761214
قاعدة البيانات:	MEDLINE

الوصف
تدمد:	0008-5472