دورية أكاديمية
Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4.
| العنوان: | Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4. |
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| المؤلفون: | Szpirer C; Département de Biologie Moléculaire, Université Libre de Bruxelles, Rhode-St-Genèse, Belgium., Szpirer J, Rivière M, Swinnen J, Vicini E, Conti M |
| المصدر: | Cytogenetics and cell genetics [Cytogenet Cell Genet] 1995; Vol. 69 (1-2), pp. 11-4. |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Karger Country of Publication: Switzerland NLM ID: 0367735 Publication Model: Print Cited Medium: Print ISSN: 0301-0171 (Print) Linking ISSN: 03010171 NLM ISO Abbreviation: Cytogenet Cell Genet Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Basel : Karger Original Publication: Basel, New York, Karger. |
| مواضيع طبية MeSH: | Chromosome Mapping* , Chromosomes, Human, Pair 1* , Chromosomes, Human, Pair 5*, 3',5'-Cyclic-AMP Phosphodiesterases/*genetics , Hominidae/*genetics , Isoenzymes/*genetics , Rats/*genetics, Animals ; Humans ; Hybrid Cells ; Mice ; Restriction Mapping |
| مستخلص: | Through the use of somatic cell hybrids segregating either human or rat chromosomes, we determined the chromosome localizations of two genes encoding cAMP-specific phosphodiesterases (cAMP-PDEs). PDE4D, the gene encoding the cAMP-PDE isoform 3 (IVd), was assigned to human chromosome 5 and rat chromosome 2, and PDE4B, the gene encoding the cAMP-PDE isoform 4 (IVb), was assigned to human chromosome 1 and rat chromosome 5. These localizations extend the homology between rat chromosome 2 and human chromosome 5, on the one hand, and between rat chromosome 5 and human chromosome 1, on the other hand. |
| معلومات مُعتمدة: | HD20788 United States HD NICHD NIH HHS |
| المشرفين على المادة: | 0 (Isoenzymes) EC 3.1.4.17 (3',5'-Cyclic-AMP Phosphodiesterases) |
| تواريخ الأحداث: | Date Created: 19950101 Date Completed: 19950227 Latest Revision: 20180214 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1159/000133927 |
| PMID: | 7835077 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0301-0171 |
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| DOI: | 10.1159/000133927 |