دورية أكاديمية
An unusual form of localized papulonodular cutaneous histiocytosis in a 6-month-old boy.
| العنوان: | An unusual form of localized papulonodular cutaneous histiocytosis in a 6-month-old boy. |
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| المؤلفون: | van Haselen CW; Department of Dermatology, University Hospital of Utrecht, The Netherlands., Toonstra J, den Hengst CW, van Vloten WA |
| المصدر: | The British journal of dermatology [Br J Dermatol] 1995 Sep; Vol. 133 (3), pp. 444-8. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Print ISSN: 0007-0963 (Print) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2023- : Oxford : Oxford University Press Original Publication: Oxford [etc.] Published for the British Association of Dermatologists by Blackwell Scientific Publications [etc.] |
| مواضيع طبية MeSH: | Histiocytosis, Non-Langerhans-Cell/*pathology , Skin Diseases/*pathology, Anti-Inflammatory Agents/therapeutic use ; Betamethasone Valerate/therapeutic use ; Histiocytosis, Non-Langerhans-Cell/drug therapy ; Humans ; Infant ; Male ; Microscopy, Electron ; Scalp Dermatoses/drug therapy ; Scalp Dermatoses/pathology ; Skin Diseases/drug therapy ; Treatment Outcome |
| مستخلص: | We report a 6-month-old boy with an unusual form of cutaneous histiocytosis. The lesions were noticed shortly after birth, and there was no evidence of systemic disease. This histiocytic disorder could not be classified according to the Histiocyte Society classification, and was therefore designated an 'unclassified' group II histiocytic disorder. The clinical picture was characterized by dark-red papulonodules with a tendency to coalesce into plaques. Histologically, the infiltrate was characterized by non-epidermotropic histiocytes showing varying degrees of differentiation, eosinophils and lymphocytes, and by the absence of foamy cells and Touton giant cells. As a most conspicuous feature, electron microscopic examination revealed laminated dense bodies, whereas Birbeck granules and comma-shaped bodies were absent. This further distinguished this uncommon variant from the well-known class II histiocytoses. During a 6-month follow-up period all the lesions showed marked regression. |
| المشرفين على المادة: | 0 (Anti-Inflammatory Agents) 9IFA5XM7R2 (Betamethasone Valerate) |
| تواريخ الأحداث: | Date Created: 19950901 Date Completed: 19960220 Latest Revision: 20190704 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1111/j.1365-2133.1995.tb02675.x |
| PMID: | 8547002 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0007-0963 |
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| DOI: | 10.1111/j.1365-2133.1995.tb02675.x |