دورية أكاديمية
Role of the alpha 1-, and alpha 2- and beta-adrenoceptors of the median preoptic area on the water intake, renal excretion, and arterial pressure induced by ANG II.
| العنوان: | Role of the alpha 1-, and alpha 2- and beta-adrenoceptors of the median preoptic area on the water intake, renal excretion, and arterial pressure induced by ANG II. |
|---|---|
| المؤلفون: | da Silva RK; Department of Physiology, School of Dentistry, Paulista State University, Araraquara, Brazil., Menani JV, Saad WA, Renzi A, Silveira JE, Luiz AC, Camargo LA |
| المصدر: | Brain research [Brain Res] 1996 Apr 22; Vol. 717 (1-2), pp. 38-43. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print Cited Medium: Print ISSN: 0006-8993 (Print) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam Elsevier/North-Holland Biomedical Press. |
| مواضيع طبية MeSH: | Angiotensin II/*physiology , Drinking/*physiology , Kidney/*physiology , Preoptic Area/*chemistry , Receptors, Adrenergic/*physiology, Adrenergic alpha-1 Receptor Antagonists ; Adrenergic alpha-2 Receptor Antagonists ; Adrenergic alpha-Antagonists/pharmacology ; Adrenergic beta-Antagonists/pharmacology ; Animals ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Drinking/drug effects ; Male ; Potassium/urine ; Prazosin/pharmacology ; Propranolol/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, Adrenergic, alpha-1/physiology ; Receptors, Adrenergic, alpha-2/physiology ; Receptors, Adrenergic, beta/physiology ; Sodium/urine ; Urination/drug effects ; Yohimbine/pharmacology |
| مستخلص: | The present experiments were conducted to investigate the role of the alpha 1-, alpha 2- and beta-adrenergic receptors of the median preoptic area (MnPO) on the water intake and urinary electrolyte excretion, elicited by central injections of angiotensin II (ANG II). Prazosin (an alpha 1-adrenergic receptor antagonist) and yohimbine (an alpha 2-adrenergic receptor antagonist) antagonized the water ingestion, Na+, K+, and urine excretion induced by ANG II. Administration of propranolol, a beta-adrenergic receptor antagonist increased the Na+, K+, and urine excretion induced by ANG II. Previous treatment with prazosin and yohimbine reduced the pressor responses to ANG II. These results suggest that the adrenergic neurotransmission in the MnPO may actively participate in ANG II-induced dipsogenesis, natriuresis, kaliuresis, diuresis and pressor responses in a process that involves alpha 1-, alpha 2-, and beta-adrenoceptors. |
| المشرفين على المادة: | 0 (Adrenergic alpha-1 Receptor Antagonists) 0 (Adrenergic alpha-2 Receptor Antagonists) 0 (Adrenergic alpha-Antagonists) 0 (Adrenergic beta-Antagonists) 0 (Receptors, Adrenergic) 0 (Receptors, Adrenergic, alpha-1) 0 (Receptors, Adrenergic, alpha-2) 0 (Receptors, Adrenergic, beta) 11128-99-7 (Angiotensin II) 2Y49VWD90Q (Yohimbine) 9NEZ333N27 (Sodium) 9Y8NXQ24VQ (Propranolol) RWP5GA015D (Potassium) XM03YJ541D (Prazosin) |
| تواريخ الأحداث: | Date Created: 19960422 Date Completed: 19961113 Latest Revision: 20190614 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/0006-8993(95)01553-1 |
| PMID: | 8738251 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0006-8993 |
|---|---|
| DOI: | 10.1016/0006-8993(95)01553-1 |