دورية أكاديمية
Technetium-99m (Tc-99m) diphosphono-propanedicarboxylic acid bone tracer uptake and Tc-99m sestamibi distribution in cardiac amyloidosis--a case report.
| العنوان: | Technetium-99m (Tc-99m) diphosphono-propanedicarboxylic acid bone tracer uptake and Tc-99m sestamibi distribution in cardiac amyloidosis--a case report. |
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| المؤلفون: | Low YH; Department of Nuclear Medicine, Singapore General Hospital., Ang ES, Goh AS, Sundram FX, Sin FL |
| المصدر: | Annals of the Academy of Medicine, Singapore [Ann Acad Med Singap] 1995 Nov; Vol. 24 (6), pp. 898-901. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academy Of Medicine, Singapore Country of Publication: Singapore NLM ID: 7503289 Publication Model: Print Cited Medium: Print ISSN: 0304-4602 (Print) Linking ISSN: 03044602 NLM ISO Abbreviation: Ann Acad Med Singap Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Singapore : Academy Of Medicine, Singapore Original Publication: Singapore. |
| مواضيع طبية MeSH: | Diphosphonates* , Organotechnetium Compounds* , Technetium Tc 99m Sestamibi* , Tomography, Emission-Computed, Single-Photon*, Amyloid Neuropathies/*diagnosis , Amyloidosis/*diagnostic imaging , Cardiomyopathies/*diagnostic imaging, Amyloid Neuropathies/pathology ; Amyloidosis/pathology ; Cardiomyopathies/pathology ; Echocardiography ; Humans ; Male ; Middle Aged ; Myocardial Infarction/pathology ; Skin/pathology ; Sural Nerve/pathology ; Tissue Survival |
| مستخلص: | It has long been recognised that significant bone tracer localisation in the myocardium is a good indicator for amyloid involvement of the heart in the clinical context of systemic amyloidosis. In this case report, although myocardial tissue diagnosis of amyloidosis was not made, the massive myocardial uptake of bone tracer strongly suggested the presence of amyloid infiltration in the heart, and this finding eventually led to the histological diagnosis of familial amyloid polyneuropathy by skin and sural nerve biopsy. Interesting findings were noted in the single photon emission computerised tomography (SPECT) studies of the myocardium with Technetium-99m diphosphono-propanedicarboxylic acid bone agent and Technetium-99m sestamibi myocardial perfusion agent. Such findings suggest that there is a lack of correlation between the intensity of myocardial uptake of bone tracer and viability of the myocardium, and that amyloid will not deposit in infarcted myocardial tissue. |
| المشرفين على المادة: | 0 (Diphosphonates) 0 (Organotechnetium Compounds) 0 (technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid) 971Z4W1S09 (Technetium Tc 99m Sestamibi) |
| تواريخ الأحداث: | Date Created: 19951101 Date Completed: 19970204 Latest Revision: 20200825 |
| رمز التحديث: | 20221213 |
| PMID: | 8839006 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0304-4602 |
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