دورية أكاديمية
A prospective clinical trial comparing metrizamide and iohexol for equine myelography.
العنوان: | A prospective clinical trial comparing metrizamide and iohexol for equine myelography. |
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المؤلفون: | Widmer WR; Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA., Blevins WE, Jakovljevic S, Levy M, Teclaw RF, Han CM, Hurd CD |
المصدر: | Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association [Vet Radiol Ultrasound] 1998 Mar-Apr; Vol. 39 (2), pp. 106-9. |
نوع المنشور: | Comparative Study; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Blackwell Country of Publication: England NLM ID: 9209635 Publication Model: Print Cited Medium: Print ISSN: 1058-8183 (Print) Linking ISSN: 10588183 NLM ISO Abbreviation: Vet Radiol Ultrasound Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Oxford : Blackwell Original Publication: Raleigh Nc : American College Of Veterinary Radiology |
مواضيع طبية MeSH: | Contrast Media*/administration & dosage , Contrast Media*/adverse effects , Horses*/classification , Iohexol*/administration & dosage , Iohexol*/adverse effects , Metrizamide*/administration & dosage , Metrizamide*/adverse effects, Horse Diseases/*diagnostic imaging , Myelography/*veterinary, Anesthesia Recovery Period ; Anesthesia, Inhalation/veterinary ; Anesthesia, Intravenous/veterinary ; Animals ; Double-Blind Method ; Female ; Fever/chemically induced ; Fever/veterinary ; Horse Diseases/chemically induced ; Male ; Myelography/methods ; Prospective Studies ; Punctures/veterinary ; Radiographic Image Enhancement ; Random Allocation ; Safety ; Seizures/chemically induced ; Seizures/veterinary ; Spinal Cord Diseases/diagnostic imaging ; Spinal Cord Diseases/veterinary |
مستخلص: | A prospective clinical trial comparing adverse postmyelographic effects and myelographic quality of metrizamide and iohexol was conducted. Using a predetermined, randomized assignment, 24 horses exhibiting neurologic signs were administered either metrizamide (180 mgl/ml) or iohexol (180 mgl/ml) via cerebellomedullary puncture. Each horse was evaluated postmyelographically for adverse effects. Myelographic quality was assessed by a numerical scoring method. Adverse effects were observed more frequently with metrizamide (21) compared with iohexol (6) myelography (p < 0.05). Seizures, intensification of preexisting neurologic signs and prolonged anesthetic recovery were the most common complications after myelography. There was no difference in myelographic quality (p > 0.05). We conclude that iohexol is safer than metrizamide for equine myelography and that quality myelograms can be obtained with either contrast medium. |
المشرفين على المادة: | 0 (Contrast Media) 4419T9MX03 (Iohexol) RHH3W8F1CO (Metrizamide) |
تواريخ الأحداث: | Date Created: 19980421 Date Completed: 19980602 Latest Revision: 20190921 |
رمز التحديث: | 20221213 |
DOI: | 10.1111/j.1740-8261.1998.tb01974.x |
PMID: | 9548136 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1058-8183 |
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DOI: | 10.1111/j.1740-8261.1998.tb01974.x |