التفاصيل البيبلوغرافية
| العنوان: |
Lutein intake at the age of 1 year and cardiometabolic health at the age of 6 years: the Generation R Study. |
| المؤلفون: |
Leermakers, Elisabeth T. M., Kiefte-de Jong, Jessica C., Hofman, Albert, Jaddoe, Vincent W. V., Franco, Oscar H. |
| المصدر: |
British Journal of Nutrition; 9/28/2015, Vol. 114 Issue 6, p970-978, 9p |
| مصطلحات موضوعية: |
ADIPOSE tissues, BLOOD pressure, BODY weight, HUMAN body composition, C-reactive protein, CARDIOVASCULAR diseases risk factors, CHOLESTEROL, CONFIDENCE intervals, HIGH density lipoproteins, INSULIN, LIPIDS, LONGITUDINAL method, LOW density lipoproteins, PROBABILITY theory, QUESTIONNAIRES, REGRESSION analysis, RESEARCH funding, STATURE, TRIGLYCERIDES, SOCIOECONOMIC factors, BODY mass index, LEAN body mass, DATA analysis software, DESCRIPTIVE statistics, LUTEIN, CHILDREN |
| مصطلحات جغرافية: |
NETHERLANDS |
| مستخلص: |
Lutein is a carotenoid with strong antioxidant properties. Previous studies in adults suggest a beneficial role of lutein on cardiometabolic health. However, it is unknown whether this relation also exists in children; therefore, we aimed to assess the relation between lutein intake at 13 months of age and cardiometabolic outcomes at the age of 6 years. We included 2044 Dutch children participating in a population-based prospective cohort study. Diet was measured at 13 months of age with an FFQ. Lutein intake was standardised for energy and β-carotene intake. Blood pressure, anthropometrics, serum lipids and insulin were measured at the age of 6 years. Dual-energy X-ray absorptiometry was performed to measure total and regional fat and lean mass. A continuous cardiometabolic risk factor score was created, including the components body fat percentage, blood pressure, insulin, HDL-cholesterol and TAG. Age- and sex-specific standard deviation scores were created for all outcomes. Multivariable linear regression was performed, including socio-demographic and lifestyle variables. Median (energy-standardised) lutein intake was 1317 mcg/d (95 % range 87, 6069 mcg/d). There were no consistent associations between lutein intake at 13 months and anthropometrics and body composition measures at 6 years of age. In addition, lutein intake was not associated with a continuous cardiometabolic risk factor score, nor was it associated with any of the individual components of the cardiometabolic risk factor score. Results from this large population-based prospective cohort study do not support the hypothesis that lutein intake early in life has a beneficial role for later cardiometabolic health. [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
Complementary Index |
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