دورية أكاديمية
Correlation Between Diastolic Dysfunction and Coronary Artery Disease on Coronary Computed Tomography Angiography.
| العنوان: | Correlation Between Diastolic Dysfunction and Coronary Artery Disease on Coronary Computed Tomography Angiography. |
|---|---|
| المؤلفون: | Jamiel, Abdelrahman, Ahmed, Amjad M., Farah, Iyad, Al-Mallah, Mouaz H. |
| المصدر: | Heart Views; Jan-Mar2016, Vol. 17 Issue 1, p13-18, 6p |
| مصطلحات موضوعية: | CORONARY disease, CORONARY artery abnormalities, CALCIUM in the body, MEASUREMENT, CORONARY angiography, CARDIAC imaging |
| مستخلص: | Aims: We investigated the relationship between coronary artery calcium score (CACS) and coronary artery disease (CAD) on coronary computed tomography angiography (CCTA), and measures of left ventricular diastolic function (DD). Methods: We included 429 consecutive patients (39% women; mean age 49 ± 12 years) without known CAD, who underwent CCTA and transthoracic echocardiography (TTE) within 1-month. Evaluation of CCTA was per vessel, and per segment basis for intraluminal diameter stenosis. We also used the 16-segment model to determine overall coronary plaque burden with segment involvement score (SIS). DD on TTE was assessed using mitral inflow E wave-to-A wave ratio (EAR) and tissue Doppler early mitral annual tissue velocity axial excursion. Results: A total of 293 (68.4%) patients had DD, 15.4% had more than stage 2 DD. The presence of DD was associated with increasing CACS (P < 0.001). Similarly, there was a statistically significant correlation between EAR and CCS (r = -0.147, P = 0.004) and SIS (r = 0.536, P < 0.001). The prevalence of more than stage 2 DD was associated with higher prevalence of obstructive CAD (26.2% vs. 11.7%, P < 0.0001). In multivariable analyses, the independent predictors of more than stage 1 DD are the age (P < 0.001), and diabetes (P = 0.010), while the CACS and SIS were not independently associated with DD. Conclusion: Our analysis suggests that CACS, as well as CAD by CCTA, are not independently associated with measures of DD on echocardiography. [ABSTRACT FROM AUTHOR] |
| Copyright of Heart Views is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| قاعدة البيانات: | Complementary Index |
Full Text Finder كن أول من يترك تعليقا!