دورية أكاديمية

Therapeutic Modulation of Calcium Dynamics Using Ultrasound and Other Energy-Based Techniques.

التفاصيل البيبلوغرافية
العنوان: Therapeutic Modulation of Calcium Dynamics Using Ultrasound and Other Energy-Based Techniques.
المؤلفون: Suarez Castellanos, Ivan Mauricio, Balteanu, Bogdan, Singh, Tania, Zderic, Vesna
المصدر: IEEE Reviews in Biomedical Engineering; 2016, Vol. 9, p177-191, 15p
مستخلص: Ultrasound, along with other types of energy-based methods, has been widely investigated for use in various therapeutic applications because of its ability to stimulate specific biological processes. Many of these processes are mediated by calcium (Ca2+) signaling, thus making modulation of Ca2+ dynamics an evident therapeutic target for energy-based techniques. Various diseases have been associated with abnormal Ca 2+ signaling and could, therefore, benefit from therapeutic approaches trying to regulate the transport of Ca2+ across cell membranes. Here, we review published literature on the use of mechanical, electrical, magnetic, and electromagnetic energy in modulating Ca2+ transients with particular emphasis on therapeutic ultrasound. We further provide brief discussions on the role of Ca2+ in living cells and the use of different experimental techniques to determine and measure its contribution to different biological processes. Finally, we explore the benefits, limitations, and potential clinical applications of different energy-based modalities that can be utilized in modulation of Ca2+ signaling. [ABSTRACT FROM PUBLISHER]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:19373333
DOI:10.1109/RBME.2016.2555760