التفاصيل البيبلوغرافية
| العنوان: |
Visceral adiposity is significantly associated with type 2 diabetes in middle-aged and elderly Chinese women: A cross-sectional study. |
| المؤلفون: |
Lv, Xiaofei, Zhou, Weiwei, Sun, Jichao, Lin, Ruhai, Ding, Lin, Xu, Min, Xu, Yu, Zhao, Zhiyun, Chen, Yuhong, Bi, Yufang, Lu, Jieli, Wang, Weiqing, Ning, Guang |
| المصدر: |
Journal of Diabetes; Oct2017, Vol. 9 Issue 10, p920-928, 9p |
| مصطلحات موضوعية: |
TYPE 2 diabetes, TYPE 2 diabetes treatment, TYPE 2 diabetes diagnosis, OBESITY complications, DIABETES risk factors, METABOLIC disorders, OBESITY |
| Abstract (English): |
Background Previous studies suggest that visceral fat is associated with type 2 diabetes ( T2D) independent of body mass index ( BMI). However, epidemiological data about the relationship between visceral fat and T2D are rare in Chinese. The aim of the present study was to investigate whether visceral fat area ( VFA) is associated with T2D beyond and above BMI in the Chinese population. Methods The present community-based cross-sectional study was conducted in 2013 on 4126 individuals (2545 women, 1581 men) aged ≥ 40 years, with T2D diagnosed according to 1999 World Health Organization criteria. The VFA was measured by a fat area analyzer using bioelectrical impedance analysis. Results Participants were categorized into normal weight and overweight/obese groups according to BMI. Within each group, compared with women with below-median VFA, women with above-median VFA had a significantly increased risk of diabetes (odds ratio [ OR] 1.88, 95% confidence interval [ CI] 1.31-2.69 in the normal weight group; OR 2.10, 95% CI 1.54-2.85 in the overweight/obese group), whereas among men the corresponding associations were not significant in either group. Among women, after multivariable adjustment including BMI, each one standard deviation increase in VFA was significantly associated with a 45% higher risk of having T2D ( OR 1.45, 95% CI 1.26-1.67), whereas among men BMI, not VFA, was independently associated with T2D ( OR 1.18, 95% CI 1.02-1.37). Conclusions Visceral fat was independently associated with T2D in women regardless of obesity status, whereas in men BMI may have a more important effect on T2D than visceral fat. [ABSTRACT FROM AUTHOR] |
| Abstract (Chinese): |
摘要 背景 既往研究提示内脏脂肪与2型糖尿病相关,且独立于体质指数(BMI)。然而在中国人群中内脏脂肪与2型糖尿病(T2D)相关性的流行病学研究较少。本研究探讨了中国人群中内脏脂肪面积(visceral fat area,VFA)与2型糖尿病的相关性以及该相关性是否独立于体质指数。 方法 在这项于2013年开展的基于社区的横断面研究中,共收集了4126名(2545名女性,1581名男性)年龄≥ 40岁的受试者,根据1999年WHO诊断标准诊断2型糖尿病。利用脂肪测量仪检测内脏脂肪面积,其原理为生物电阻抗法。 结果 根据体质指数将受试者分为正常体重组和超重/肥胖组。在每组内,相比于内脏脂肪在中位数以下的女性,内脏脂肪在中位数以上的女性2型糖尿病患病风险显著升高(正常体重组比值比为1.88,95% CI 1.31-2.69;超重/肥胖组的比值比为2.10,95% CI 1.54-2.85),然而在男性中,该相关性无显著统计学意义。在女性中,校正了包括体质指数等多种危险因素后,内脏脂肪面积每增加一个标准差,2型糖尿病的患病风险增加45%(比值比为1.45,95% CI 1.26-1.67),相反在男性中,体质指数是2型糖尿病患病风险的独立危险因素(比值比为1.18,95% CI 1.02-1.37),而不是内脏脂肪面积。 结论 在女性中,内脏脂肪是独立于肥胖的2型糖尿病危险因素,而在男性中,体质指数可能比内脏脂肪对2型糖尿病的患病风险有更重要的作用。 [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
