التفاصيل البيبلوغرافية
| العنوان: |
Streptococcus pneumoniae: distribution of serotypes and antimicrobial susceptibility in patients with cancer. |
| المؤلفون: |
Soto-Noguerón, Araceli, Carnalla-Barajas, María Noemí, Cornejo-Juárez, Patricia, Volkow-Fernández, Patricia, Velázquez-Meza, María Elena, Echániz-Aviles, Gabriela |
| المصدر: |
Salud Pública de México; ene/feb2018, Vol. 60 Issue 1, p21-28, 8p, 1 Chart, 3 Graphs |
| مصطلحات موضوعية: |
SEROTYPES, COMMUNICABLE diseases, HEMATOLOGIC malignancies, PNEUMOCOCCAL vaccines, CANCER patients, PATIENTS, VACCINES |
| Abstract (English): |
Objective. To describe the distribution of pneumococcal serotypes causing infectious diseases in patients with hematological malignancies and solid tumors and their antimicrobial susceptibility before and after introduction of pneumococcal conjugate vaccine (PCV7) in Mexico. Materials and methods. Consecutive pneumococcal isolates from hospitalized patients from the SIREVA-network were serotyped using the Quellung reaction and antimicrobial susceptibility was performed using the broth microdilution method. Results. A total of 175 pneumococcal isolates were recovered, 105 from patients with hematological malignancies and 70 with solid tumors. Serotypes 19A (22.7%), 19F (20.4%), and 35B (17.7%) were the most frequent isolates in the first group and serotypes 3 (27.2%) and 19A (28.6%) in the second group. No decreased susceptibility to beta-lactams or TMP/SMX was observed after introduction of PCV7. Conclusions. An increase in non-vaccine types is observed without significate changes in antimicrobial susceptibility after introduction of PCV7. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Objetivo. Describir la distribución de serotipos neumocócicos en pacientes con neoplasias hematológicas y tumores sólidos, así como la susceptibilidad antimicrobiana antes y después de la introducción de la vacuna conjugada contra neumococo (PCV7) en México. Material y métodos. Se tipificaron, mediante la reacción de Quellung, los aislamientos consecutivos en hospitales de la Red SIREVA-México. Se determinó la susceptibilidad antimicrobiana mediante microdilución en placa. Resultados. Se recuperaron 175 aislamientos, de los cuales 105 provenían de pacientes con neoplasias hematológicas y 70 con tumores sólidos. Los serotipos 19A (22.7%), 19F (20.4%) y 35B (17.7%) fueron los más frecuentes en el primer grupo y los serotipos 3 (27.2%) y 19A (28.6%) en el segundo. No se observó disminución de la resistencia a betalactámicos o TMP/SMX después de la introducción de PCV7. Conclusiones. Se observa un incremento de serotipos no vacunales, sin cambios significativos en la susceptibilidad antimicrobiana antes y después de la introducción de PCV7. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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