التفاصيل البيبلوغرافية
| العنوان: |
Tomentodione E, a new sec-pentyl syncarpic acid-based meroterpenoid from the leaves of Rhodomyrtus tomentosa. |
| المؤلفون: |
Liu, Jie, Song, Jian-Guo, Su, Jun-Cheng, Huang, Xiao-Jun, Ye, Wen-Cai, Wang, Ying |
| المصدر: |
Journal of Asian Natural Products Research; Jan2018, Vol. 20 Issue 1, p67-74, 8p |
| مصطلحات موضوعية: |
FOLIAR diagnosis, BIOLOGICAL assay, MASS spectrometry, MOLECULAR structure, NUCLEAR magnetic resonance spectroscopy, RESEARCH funding, RESPIRATORY syncytial virus, RIBAVIRIN, TERPENES, RESPIRATORY syncytial virus infections, IN vitro studies |
| مستخلص: |
A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessing a sec-pentyl syncarpic acid motif coupled with a caryophyllene. Compounds 1-4 were evaluated for their in vitro antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect (CPE) reduction assay, and 2 showed potent in vitro anti-RSV effect. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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