دورية أكاديمية

Effect of Omega-3 Fatty Acids on Chronic Periodontitis Patients in Postmenopausal Women: A Randomised Controlled Clinical Study.

التفاصيل البيبلوغرافية
العنوان: Effect of Omega-3 Fatty Acids on Chronic Periodontitis Patients in Postmenopausal Women: A Randomised Controlled Clinical Study.
المؤلفون: Elgendy, Enas Ahmed, Kazem, Hazem Hussein
المصدر: Oral Health & Preventive Dentistry; 7/1/2018, Vol. 16 Issue 4, p327-332, 6p, 1 Diagram, 1 Chart
مصطلحات موضوعية: OMEGA-3 fatty acids, PERIODONTITIS, POSTMENOPAUSE, SUPEROXIDE dismutase, DEBRIDEMENT, DIETARY supplements, CHRONIC disease treatment, PERIODONTITIS treatment, COMPARATIVE studies, DENTAL scaling, EXUDATES & transudates, RESEARCH methodology, MEDICAL cooperation, PERIODONTAL pockets, RESEARCH, TOOTH root planing, EVALUATION research, RANDOMIZED controlled trials, BLIND experiment
مستخلص: Purpose: To investigate changes in periodontal parameters and superoxide dismutase activity after root surface debridement with and without omega-3 fatty acid (omega-3 FA) supplementation in postmenopausal women.Materials and Methods: Fifty postmenopausal women with chronic periodontitis were divided randomly into two groups. Group 1 (control group, n = 25) patients were provided with periodontal treatment in the form of scaling and root planing (SRP) plus soft gelatinous capsules containing only some olive oil, while group 2 (n = 25) received SRP along with systemic administration of omega-3 FAs in the same soft gelatinous capsules. Clinical parameters and superoxide dismutase (SOD) activity in the gingival crevicular fluid were recorded at baseline, 3 and 6 months after therapy.Results: By the end of the study period, the omega-3-treated group achieved a greater mean probing pocket depth reduction, a mean gain in clinical attachment level especially in deep periodontal pockets, as well as a greater increase in SOD activity (p < 0.01) compared to SRP alone.Conclusions: Adjunctive omega-3 FAs supplements with SRP reduce periodontal inflammation and improve the status of systemic enzymatic antioxidants in postmenopausal women. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:16021622
DOI:10.3290/j.ohpd.a40957