Palivizumab for Infants < 29 Weeks in Hong Kong without a Clear-Cut Season for Respiratory Syncytial Virus Infection-A Cost-Effectiveness Analysis.

التفاصيل البيبلوغرافية
العنوان:	Palivizumab for Infants < 29 Weeks in Hong Kong without a Clear-Cut Season for Respiratory Syncytial Virus Infection-A Cost-Effectiveness Analysis.
المؤلفون:	Lee, Shing-Yan Robert, Kwok, Ka Li, Ng, Daniel Kwok Keung, Hon, Kam Lun
المصدر:	Journal of Tropical Pediatrics; Oct2018, Vol. 64 Issue 5, p418-425, 8p
مصطلحات موضوعية:	RESPIRATORY syncytial virus, INFANT diseases, PREMATURE infants, RESPIRATORY syncytial virus infections, PALIVIZUMAB
مستخلص:	Aim: To evaluate the cost-effectiveness of palivizumab prophylaxis for premature infants born <29 weeks in Hong Kong.Method: We evaluated the hospitalization rate for respiratory syncytial virus (RSV) infection within the first 12 months of discharge of a cohort of preterm infants born between 2010 and 2014 at two local hospitals.Results: In total, 40 of 135 infants were given palivizumab. The hospitalization rate for premature infants <29 weeks was reduced from 15.8 to 5% (p = 0.096) and that for infants <27 weeks was reduced from 33.3 to 8.7% (p = 0.046). In the former group, the incremental cost-effectiveness ratio per hospital admission prevented (ICER/HAP) was US dollar (USD) 24 365. In the latter subgroup, the ICER/HAP was USD 3108.Conclusion: The cost-effectiveness as measured for infants <27 weeks is more favorable than that for infants <29 weeks. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات:	Complementary Index

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