دورية أكاديمية
Synthesis, characterization and antimicrobial evaluation of N-(4-oxo-2phenyl/thiophenylquinazolin-3(4H)-yl)-1H-indole-2 or 3-carboxamide derivatives.
| العنوان: | Synthesis, characterization and antimicrobial evaluation of N-(4-oxo-2phenyl/thiophenylquinazolin-3(4H)-yl)-1H-indole-2 or 3-carboxamide derivatives. |
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| المؤلفون: | Chaudhary, Aniruddh Prasad, Shukla, Akhilesh Kumar, Kant, Padam |
| المصدر: | Chemistry & Biology Interface; Nov/Dec2018, Vol. 8 Issue 6, p359-372, 14p |
| مصطلحات موضوعية: | ANTI-infective agents, BACTERIA, ELECTRONS, CARBOXAMIDES, NUCLEAR magnetic resonance |
| مستخلص: | A series of novel N-(4-oxo-2phenyl/thiophenylquinazolin-3(4H)-yl)-1H-indole-2 or 3-carboxamide derivatives were prepared and screened for their antimicrobial activities against different strains of bacteria and fungi. The most potent antibacterial and antifungal activity was exhibited by compound 5d & 5h with halogen substituted ring in the respective series compared to the compounds bearing other electron donating or withdrawing groups. The synthesized compounds were characterized with the help of spectroscopic techniques including IR, 1H-NMR, 13C-NMR and Mass spectra. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
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