دورية أكاديمية
Vitamin E supplementation and risk of coronary artery disease in women.
| العنوان: | Vitamin E supplementation and risk of coronary artery disease in women. |
|---|---|
| المؤلفون: | Sontakke, Alka, Dhat, Vaishali, Trimbake, Sangeeta, Nutan, Chaudhari, Sayyed, Anjum |
| المصدر: | Indian Journal of Basic & Applied Medical Research; Sep2019, Vol. 8 Issue 4, p198-206, 9p |
| مصطلحات موضوعية: | VITAMIN E, CORONARY disease, BLOOD lipids, BLOOD cholesterol, RURAL health |
| مصطلحات جغرافية: | INDIA |
| مستخلص: | Introduction- Increase in prevalence of Coronary artery disease (CAD) in India warrants probing into the presence of various risk factors and their association with CAD. Traditional risk factors such as age, family history of CAD, hypertension, diabetes, dyslipidemia, smoking, and physical inactivity are predictors of risk in women. The recent risk factors with controversial status as individual risk factors are serum lp(a) and serum hsCRP which need to be addressed. Hence this study was designed to assess the response of traditional and recent risk factors to supplementation of vitamin E in women of reproductive age group. Material and Methods- 106 women in reproductive age (18- 45 years) were screened from MIMER Medical College and Rural Health Training Centre for the parameters like serum lipid profile, MDA (malondialdehyde), Vitamin E, hsCRP and lipoprotein(Lp) (a). Vitamin E supplementation 400mg for 45 days was given to women in whom one or more parameters were found to be abnormal and the parameters were re-estimated. Result- There was a significant fall in the serum total cholesterol and LDL levels after vitamin E supplementation in affected women. The levels of serum triacylglycerol, hsCRP, Lp(a) and MDA decreased and HDL, vitamin E levels increased insignificantly after supplementation in the affected females. Conclusion- Screening of women in reproductive age group for lipid profile, Lp(a) and hsCRP would help to identify the risk factors for CAD. These women could be administered vitamin E so that the risk of developing CAD would be minimized in them. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
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