دورية أكاديمية
Coinfection with Human Norovirus and Escherichia coli O25:H4 Harboring Two Chromosomal blaCTX-M-14 Genes in a Foodborne Norovirus Outbreak in Shizuoka Prefecture, Japan.
| العنوان: | Coinfection with Human Norovirus and Escherichia coli O25:H4 Harboring Two Chromosomal blaCTX-M-14 Genes in a Foodborne Norovirus Outbreak in Shizuoka Prefecture, Japan. |
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| المؤلفون: | HIROMI NAGAOKA, SHINICHIRO HIRAI, HIROTAKA MORINUSHI, SHIRO MIZUMOTO, KANA SUZUKI, HIROAKI SHIGEMURA, NAOTO TAKAHASHI, FUMIE SUZUKI, MIZUHA MOCHIZUKI, MICHIKO ASANUMA, TAKAHARU MAEHATA, AYA OGAWA, KAI OHKOSHI, TSUYOSHI SEKIZUKA, TAISEI ISHIOKA, SATOWA SUZUKI, HIROKAZU KIMURA, MAKOTO KURODA, MOTOI SUZUKI, KOICHI MURAKAMI |
| المصدر: | Journal of Food Protection; Sep2020, Vol. 83 Issue 9, p1584-1591, 8p, 2 Diagrams, 3 Charts, 1 Graph |
| مستخلص: | Hospital-acquired infections caused by extended-spectrum β-lactamase (ESBL)–producing Escherichia coli are a global problem. Healthy people can carry ESBL-producing E. coli in the intestines; thus, E. coli from healthy people can potentially cause hospital-acquired infections. Therefore, the transmission routes of ESBL-producing E. coli from healthy persons should be determined. A foodborne outbreak of human norovirus (HuNoV) GII occurred at a restaurant in Shizuoka, Japan, in 2018. E. coli O25:H4 was isolated from some of the HuNoV-infected customers. Pulsed-field gel electrophoresis showed that these E. coli O25:H4 strains originated from one clone. Because the only epidemiological link among the customers was eating food from this restaurant, the customers were concurrently infected with E. coli O25:H4 and HuNoV GII via the restaurant food. Whole genome analysis revealed that the E. coli O25:H4 strains possessed genes for regulating intracellular iron and expressing the flagellum and flagella. Extraintestinal pathogenic E. coli often express these genes on the chromosome. Additionally, the E. coli O25:H4 strains had plasmids harboring nine antimicrobial resistance genes. These strains harbored ESBL-encoding bla |
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| قاعدة البيانات: | Complementary Index |
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