دورية أكاديمية
An Overview of Immunoglobulin G4-related Ophthalmic Diseases Accompanied by a Case Report.
| العنوان: | An Overview of Immunoglobulin G4-related Ophthalmic Diseases Accompanied by a Case Report. |
|---|---|
| المؤلفون: | ŞİMŞEK, Bengü ÇOBANOĞLU, CECİKOĞLU, Gözde Ecem, DURMUŞ, Ebubekir, ORHAN SÖYLEMEZ, Umut Perçem |
| المصدر: | Türkiye Klinikleri Journal of Case Reports; 2021, Vol. 29 Issue 1, p33-37, 5p |
| مصطلحات موضوعية: | IMMUNOGLOBULIN G, PLASMA cell diseases, EYE diseases, HISTOPATHOLOGY, EOSINOPHIL disorders |
| مستخلص: | Immunoglobulin G4-related diseases (IgG4-RDs) are immune-mediated, fibroinflammatory conditions that are characterised by affected organ enlargement, lymphocyte, plasma cell infiltration (determined with IgG4-positive plasma cells) and serum IgG4 level elevation. When the disease affects ocular adnexal tissues (such as the lacrimal gland, extraocular muscles, trigeminal nerve branches and orbital fat), it is called IgG4-related ophthalmic disease (IgG4-ROD). The diagnosis of IgG4-ROD is made by physical examination, biochemical findings and histopathological evaluation. It is characterized by elevated serum IgG4 levels and distinctive histopathological features, including IgG4+ plasma cell infiltration, the presence of fibrosis in the storiform pattern and the presence of a dense lymphoplasmacytic inflammatory infiltrate, including eosinophils. It is rare in the ocular region and cause diagnostic confusion. There is a high probability of misdiagnosis when the disease is not recognized. Here, a rare case of eye involvement is presented and IgG4-RDs are discussed with the literature. [ABSTRACT FROM AUTHOR] |
| Copyright of Türkiye Klinikleri Journal of Case Reports is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| قاعدة البيانات: | Complementary Index |
كن أول من يترك تعليقا!