التفاصيل البيبلوغرافية
| العنوان: |
A New Brominated Norsesquiterpene Glycoside From the Rhizomes of Acorus tatarinowii Schott. |
| المؤلفون: |
Zhi-You Hao, Gang Ni, Dong Liang, Yan-Fei Liu, Chun-Lei Zhang, Yan Wang, Qing-Jian Zhang, Ruo-Yun Chen, De-Quan Yu |
| المصدر: |
Natural Product Communications; Feb2021, Vol. 16 Issue 2, p1-6, 6p |
| مصطلحات موضوعية: |
GLYCOSIDES, ACORALES, ROTENONE, CIRCULAR dichroism, NERVE growth factor |
| مستخلص: |
A new brominated norsesquiterpene glycoside, acoruside (1), has been isolated from the rhizomes of Acorus tatarinowii Schott, together with 8 known compounds (2-9). Their structures were elucidated mainly based on 1-dimensional (1D) and 2D nuclear magnetic resonance spectra. The absolute configuration of compound 1 was determined by comparing its experimental and calculated electronic circular dichroism spectra. The in vitro tests indicated that at 10 μM, compounds 2, 3, and 4 aggravated serum deprivation injuries of PC12 cells, compound 2 aggravated rotenone-induced injuries of PC12 cells, and compounds 3 and 4 aggravated the oxygen-glucose deprivation-induced injuries of PC12 cells. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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