التفاصيل البيبلوغرافية
| العنوان: |
Probiotics on Intestinal Flora Disturbance and Bacterial Translocation in Mice with Inflammatory Bowel Disease. |
| المؤلفون: |
LIYING DING, XIUTING CHEN, QIAN, K., JIANG, Z. |
| المصدر: |
Indian Journal of Pharmaceutical Sciences; Nov/Dec2021, Vol. 83 Issue 6, p1174-1180, 7p |
| مصطلحات موضوعية: |
INFLAMMATORY bowel diseases, PROBIOTICS, BOTANY, CLOSTRIDIUM perfringens, LACTOBACILLUS plantarum, INTESTINES, MICE, ENTEROBACTER |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
Inflammatory bowel disease is becoming more and more common in western countries and less common in China. However, with the change of dietary structure, the incidence of inflammatory bowel disease is also increasing in China. It will cause abdominal pain, diarrhea and mucus, pus and blood, which are repeatedly delayed and difficult to alleviate. To explore the effectiveness of probiotics in the treatment of inflammatory bowel disease, Lactobacillus plantarum in probiotics and fifteen 8 w old female mice were selected for the experiment. We divided the mice into three groups: blank control group, interleukin-10 group and interleukin-10+Lactobacillus plantarum group. The interleukin-10+Lactobacillus plantarum group was gavaged with 0.5 ml of Lactobacillus plantarum bacterial solution (1.0×109 CFU/ml) every d. The blank control group and interleukin-10 group were gavaged with 0.5 ml of Ringer buffer for 4 consecutive w and compared the changes caused by Lactobacillus plantarum on Bifidobacterium, Lactobacillus, Clostridium perfringens and Enterobacter in the intestinal flora of mice and the changes caused by Lactobacillus plantarum on the intestinal flora effect of bacterial translocation in membranous lymph nodes and spleen. We found that the content of Enterobacter in the blank control group was the lowest at all three time points, with an average of 6. The content of Enterobacter in the interleukin-10+Lactobacillus plantarum group and the interleukin-10 group was 6.5 and 6.6 respectively, at the beginning of 0 w and 6.3 at the beginning of 2 w but after the 4 w, the content of Enterobacter in the two groups became 6.4 and 6.7, the difference increasedy. [ABSTRACT FROM AUTHOR] |
|
Copyright of Indian Journal of Pharmaceutical Sciences is the property of Indian Journal of Pharmaceutical Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
