التفاصيل البيبلوغرافية
| العنوان: |
Four new fatty acid derivatives from Diaporthe sp. T24, an endophytic fungus isolated from Ligularia fischer. |
| المؤلفون: |
He, Min, Yin, Wan-Qiang, Sun, Hai-Feng, Ding, Yu-Wei, Xu, Shuai, Sun, Hua, Wang, Jia-Ming, Yu, Peng, Qin, Hai-Juan, Chen, Ming-Hua |
| المصدر: |
Journal of Asian Natural Products Research; Jul2022, Vol. 24 Issue 7, p603-616, 14p |
| مصطلحات موضوعية: |
FATTY acid analysis, CARBOXYLIC acids analysis, MEDICINAL plants, BIOLOGICAL products, HIGH performance liquid chromatography, FUNGI, ANTINEOPLASTIC agents, NUCLEAR magnetic resonance spectroscopy, COMPARATIVE studies, PLANT stems, CARBOXYLIC acids, RESEARCH funding, DESCRIPTIVE statistics, MASS spectrometry, CELL lines, MOLECULAR structure, FATTY acids, METABOLITES, PHARMACODYNAMICS |
| مستخلص: |
The endophytic fungus Diaporthe sp. is known to contain many secondary metabolites, but fatty acid derivatives have rarely been found. In this study, four new fatty acid derivatives (1–4), together with four known compounds (5–8), were isolated from Diaporthe sp., which was obtained from the stem of Ligularia fischeri. The absolute configurations of the new compounds 1–4 were deduced based on spectroscopic technique and J-based coupling constant analysis. Moreover, compound 1 exhibited cytotoxic activities against HCT-8 and MCF-7 cancer cells, and compounds 3 and 4 showed modest selectivity for HCT-8 cells by MTT assay. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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