التفاصيل البيبلوغرافية
| العنوان: |
Galektin 3 ve Vitronektinin Koroner Stent Restenozu ile İlişkisi. (Turkish) |
| Alternate Title: |
Association of Coronary in-Stent Restenosis with Serum Galectin 3 and Vitronectin Levels. (English) |
| المؤلفون: |
ÖZPAMUK KARADENİZ, Fatma, ALTUNTAŞ, Emine, MİHMANLI, Müjgan, EREN, Mehmet |
| المصدر: |
MN Cardiology / MN Kardiyoloji; 2022, Vol. 29 Issue 3, p109-115, 7p |
| مصطلحات موضوعية: |
CORONARY restenosis, VITRONECTIN, CORONARY angiography, HOSPITAL records, CROSS-sectional method |
| Abstract (English): |
Objective: The aim of this study is to assess the association between vitronectin, galectin 3 levels in coronary in‐stent restenosis pa‐ tients. Material and Method: Our study is a retrospective cross‐sectional study. A total of 73 patients who had coronary stent implantation and follow‐up coronary angiography were included in the study. Of these, 48 were in the in‐stent restenosis group and 25 were in the control group without restenosis. Vitronectin and galectin 3 levels were studied with the ELISA method. The clinical, demographic and laboratory data of the patients were recorded from the hospital records. Results: Vitronectin level was 39 μg/mL in the in‐stent restenosis group and 34,55 μg/mL in the control group, and it was found to be significantly higher in those with in‐stent restenosis (p=0.024). Galectin 3 level was 11.9 ng/mL in the in‐stent restenosis group and 11.2 ng/mL in the control group, and it was found to be significantly higher in the in‐stent restenosis group (p=0.005). There was no signifi‐ cant difference between the two groups in terms of clinical, demographic and laboratory parameters except hypertension. Conclusion: The higher levels of vitronectin and galectin 3 are associated with coronary stent restenosis. [ABSTRACT FROM AUTHOR] |
| Abstract (Turkish): |
Amaç: Koroner artere stent yerleştirilmesi yapılan hastalarda galektin 3 ve vitronektin düzeylerinin stent içi restenozuna olan etkisini araştırmak. Gereç ve Yöntem: Çalışmamız geriye dönük kesitsel bir çalışmadır. Çalışmaya daha önce koroner stent takılan ve takip anjiyoları olan 73 hasta alındı. Hastalar stent içi restenozu gelişenler ve gelişmeyenler olarak iki gruba ayrıldı. Bunlardan 48’inde stent içi restenozu saptanan gruba, kalan 25’i stent içi restenozu saptanmayan kontrol grubuna alındı. Vitronektin ve galektin 3 seviyeleri ELISA metodu ile çalışıldı. Hastaların klinik, demografik ve laboratuvar verileri hastane kayıtlarından kaydedildi. Bulgular: Vitronektin düzeyi stent içi restenozu grubunda ortalama 39μg/mL, kontrol grubunda 34,55 μg/mL olup, stent içi restenozu olanlarda anlamlı derecede yüksek saptandı (p=0,024). Galektin 3 düzeyi stent içi restenozu grubunda 11,9 ng/mL, kontrol grubunda 11,2 ng/mL olup, stent içi restenozu grubunda anlamlı olarak yüksek saptandı (p=0,005). İki grup arasında hipertansiyon dışındaki kli‐ nik, demografik ve laboratuvar parametreleri açısından anlamlı fark saptanmadı. Sonuç: Koroner stent içi restenozu gelişmiş hastalarda vitronektin ve galektin 3 düzeyleri anlamlı olarak yüksek saptandı. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
