دورية أكاديمية
Endovascular Surgery of Descending Thoracic Aorta Involved in T4 Lung Tumor.
العنوان: | Endovascular Surgery of Descending Thoracic Aorta Involved in T4 Lung Tumor. |
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المؤلفون: | Di Tommaso, Luigi, Di Tommaso, Ettorino, Giordano, Raffaele, Mileo, Emilio, Santini, Mario, Pilato, Emanuele, Iannelli, Gabriele |
المصدر: | Journal of Endovascular Therapy; Feb2023, Vol. 30 Issue 1, p84-90, 7p |
مستخلص: | Purpose: Surgical treatment of primary lung T4 tumors is controversial especially when the cancer invades the mediastinal structures or the descending thoracic aorta. Conventional surgical treatment is associated with a high perioperative mortality and morbidity rate. Thoracic EndoVascular Aortic Repair has emerged as a valid off-label alternative to conventional surgery. We aimed to assess perioperative and midterm aortic-related outcome of patients who have undergone aortic stent-graft implantation, followed by en bloc surgical treatment of the involved aorta and lung cancer resection. Materials and Methods: From July 2017 to May 2020, we treated 5 patients diagnosed with a T4 lung cancer by the involvement of the descending thoracic aorta. When only the descending thoracic aorta is involved, a 2-stage procedure was considered, with aortic stent-graft implantation performed before tumor resection. One-stage strategy, with stent-graft implantation carried out before thoracotomy, was preferred for patients with the involvement of cardiac and/or other vascular mediastinal structures. Results: The mean age was 58.4 ± 6.2 years. All patients were affected by non–small cell lung cancer. All 5 patients required a single stent-graft to completely cover the involved segment of aorta. Four patients underwent a 2-stage procedure. One patient, with the involvement of the left inferior pulmonary vein, required a 1-stage en bloc resection of the left lower lobe, aortic wall adventitia, left inferior pulmonary vein, and reconstruction of the left atrial wall. Primary procedural success was achieved in all. At follow-up, no patient developed aortic-related complications. One patient died 2 years after surgery, due to local recurrence of the tumor. Conclusion: T4 lung resection combined with aortic stent-graft implantation can be safely performed. Endovascular surgery, by avoiding the use of cardiopulmonary bypass, aortic cross-clamping, and graft replacement, can reduce significant morbidity and mortality rate. Postoperative and long-term outcome of these patients treated with endovascular surgery is mainly related to pulmonary disease, not to aortic treatment. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: | Complementary Index |
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