التفاصيل البيبلوغرافية
| العنوان: |
Behavioral and emotional difficulties and HIV treatment outcomes among HIV-infected children in rural southwestern China. |
| المؤلفون: |
Zhou, Yesheng, Tang, Kailing, Lu, Hongyan, Chen, Hongli, Xie, Haomin, Li, Zeyu, Huang, Jinghua, Fang, Ningye, Chen, Siya, Wang, Hong, He, Qin, Chen, Huanhuan, Liu, Xiu, Lan, Guanghua, Zhu, Qiuying, Chen, Yi, Zhang, Xiangjun, Ruan, Yuhua, Liang, Shujia |
| المصدر: |
Child & Adolescent Psychiatry & Mental Health; 4/18/2023, Vol. 17 Issue 1, p1-10, 10p |
| مصطلحات موضوعية: |
HIV infections & psychology, CLINICAL drug trials, HIV infection prognosis, HIV infections, SOCIAL support, CONFIDENCE intervals, CROSS-sectional method, SELF-evaluation, MULTIPLE regression analysis, RURAL conditions, VIRAL load, ANTIRETROVIRAL agents, BEHAVIOR disorders in children, TREATMENT effectiveness, T-test (Statistics), SEX distribution, AFFECTIVE disorders, RESEARCH funding, QUESTIONNAIRES, DESCRIPTIVE statistics, CHI-squared test, PATIENT compliance, PARENT-child relationships, DATA analysis software, RURAL population, PSYCHOLOGY of HIV-positive persons, EVALUATION, CHILDREN |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
Background: Previous studies have not clearly demonstrated the impact of behavioral and emotional problems (BEDs) on treatment outcomes among HIV-infected children on antiretroviral therapy (ART). This study aimed to describe the prevalence of BEDs among this population and identify the factors associated with HIV treatment outcomes. Methods: This cross-sectional study was conducted in Guangxi, China, between July and August 2021. HIV-infected children answered questionnaires about BEDs, physical health, social support, and whether they have missed doses in the past month. BEDs were assessed using the Chinese version of the self-reported Strengths and Difficulties Questionnaire (SDQ-C). The self-reported survey data were linked to participants' HIV care information that was obtained from the national surveillance database. Univariate and multivariate logistic regression models were used to identify factors that were associated with missed doses in the past month and virological failure. Results: The study sample was 325 HIV-infected children. HIV-infected children had a higher proportion of abnormal scores on SDQ-C total difficulties compared to their peers in the general population (16.9 vs 10.0%; P = 0.002). An abnormal SDQ-C total difficulties score (AOR = 2.06, 95%CI: 1.10–3.88) and infrequency of receiving assistance and support from parents over the past 3 months (AOR = 1.85, 95%CI: 1.12–3.06) were significantly associated with missed doses in the past month. Between the ages of 14–17 years (AOR = 2.66, 95% CI: 1.37–5.16), female (AOR = 2.21, 95% CI: 1.20–4.08), and suboptimal adherence (AOR = 2.45, 95% CI: 1.32–4.57) were significantly associated with virological failure. Conclusions: Children's mental health plays a role in HIV treatment outcomes. Psychological interventions should be promoted in pediatric HIV care clinics to improve children's mental health status and HIV treatment outcomes. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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