التفاصيل البيبلوغرافية
| العنوان: |
Small volume biopsy diagnostic yield at initial diagnosis versus recurrence/transformation of follicular lymphoma: A retrospective Cyto‐Heme Interinstitutional Collaborative study. |
| المؤلفون: |
Fitzpatrick, Megan J., Sundaram, Vandana, Ly, Amy, Abramson, Jeremy S., Balassanian, Ronald, Cheung, Matthew C., Cook, Stephen L., Falchi, Lorenzo, Frank, Annabel K., Gupta, Srishti, Hasserjian, Robert P., Lin, Oscar, Long, Steven R., Menke, Joshua R., Mou, Eric, Reed, Daniel R., Ruiz‐Cordero, Roberto, Volaric, Ashley K., Wang, Linlin, Wen, Kwun Wah |
| المصدر: |
Cancer Cytopathology; May2023, Vol. 131 Issue 5, p279-288, 10p |
| مستخلص: |
Background: Few studies have evaluated diagnostic yield of small volume biopsies (SVB) for the diagnosis and management of follicular lymphoma (FL). Methods: The authors performed a multi‐institutional retrospective analysis of SVBs including fine‐needle aspiration (FNA) and needle core biopsy (NCB) for initial FL diagnosis and suspected recurrence or transformation of FL. A total of 676 workups beginning with SVB were assessed for the mean number of biopsies per workup, the proportion of workups requiring multiple biopsies, and the proportion with a complete diagnosis including grade, on initial biopsy. Results: Compared to workups performed for question transformation/recurrence, those done for initial FL diagnosis were significantly more likely to require multiple biopsies (p <.01), had a higher mean number of biopsies per workup (1.7 vs. 1.1, absolute standardized difference = 1.1), and a lower complete diagnosis rate at initial biopsy (39% vs. 56%). At initial FL diagnosis, NCB +/− FNA was associated with fewer biopsies per workup compared to FNA +/− CB (1.2 vs. 1.9), fewer workups requiring multiple biopsies (23% vs. 83%), and a higher complete diagnosis rate (71% vs. 18%). In contrast, during assessment for transformation/recurrence, NCB and FNA showed a similar mean number of biopsies per workup (1.2 vs. 1.2) and few workups required multiple biopsies (6% vs. 19%). Conclusions: SVB at initial FL diagnosis often required additional biopsies to establish a complete diagnosis. In contrast, when assessing for transformed/recurrent FL, additional biopsies were generally not obtained regardless of SVB type, suggesting that in these clinical settings SVB may be sufficient for clinical decision‐making. Small volume biopsies obtained for initial diagnosis of follicular lymphoma are likely to require a subsequent biopsy, especially when fine–needle aspiration‐based procedures are performed. In contrast, small volume biopsies performed to determine follicular lymphoma recurrence or transformation infrequently requires a subsequent biopsy regardless of biopsy type. [ABSTRACT FROM AUTHOR] |
|
Copyright of Cancer Cytopathology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder