التفاصيل البيبلوغرافية
| العنوان: |
Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization in Infantile Hydrocephalus: An Experience from Mali. |
| المؤلفون: |
Diallo, Oumar, Dama, Mahamadou, Konan, Landry, Coulibaly, Oumar, Sissoko, Daouda, Maiga, Abdoulaye Hima |
| المصدر: |
Pediatric Neurosurgery; 2023, Vol. 58 Issue 1, p38-44, 7p |
| مصطلحات موضوعية: |
CHOROID plexus, HYDROCEPHALUS, HUMAN abnormalities, AGE groups, CAUTERY, TREATMENT effectiveness, CEREBROSPINAL fluid shunts |
| مصطلحات جغرافية: |
MALI, SUB-Saharan Africa |
| مستخلص: |
Introduction: Pediatric hydrocephalus is a common disease in sub-Saharan Africa. In Mali, 350–400 new cases are diagnosed in our center yearly. With a total land mass of 1,241,000 km2, patients in remote areas must travel up to 1,500 km to access neurosurgical care. Hence, treatment and follow-ups of "shunted" patients are difficult. In this context, endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) provides an opportunity for an affordable and less constraining treatment for hydrocephalus children under 12 months of age. Methods: We performed a retrospective analysis of ETV/CPC performed on infants from July 2013 to January 2015. Patients were followed postoperatively on day 15, month 6, and month 12. Statistical analysis was conducted using Prism 9 GraphPad software. ETV successes were categorized according to the patient's age into 3 groups: ≤3 months, 3–6 months, and 6–12 months. Statistical significance was defined at p < 0.05. Results: During the study period, 199 patients were included with 40% of patients aged between 0 and 6 months. The head circumference ranged from 35 cm to 79 cm. The etiology was congenital malformation in 55%. ETV/CPC was a success in 69% of 6- to 12-month-old patients, 54% in the 3- to 6-month-old patients, and 29% in ≤3-month-old patients. Overall, 94 (47%) patients were successfully treated without a shunt. The postoperative infection rate was 1% and mortality at 12 months was 8%. Conclusion: In a low-income environment such as Mali, ETV/CPC stands as a viable and alternative treatment option for pediatric hydrocephalus patients; our findings suggest that age is an important factor in predicting ETV success. [ABSTRACT FROM AUTHOR] |
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