التفاصيل البيبلوغرافية
| العنوان: |
SAR444245, a non‐alpha IL2, rescues chronic antigen and CAR‐driven T‐cell dysfunction. |
| المؤلفون: |
Sheikh, I., Choi, A., Reville, P. K., Henderson, J., Rojas, E., Le, C., Okwuchi, C., Carrio, R., Pate, N., Malley, K., Bangari, D., Gavigan, J., Shi, C., Liu, B., Byers, T., Sassoon, I., Cucchetti, M., Wang, R., Agarwal, M., Abbadessa, G. |
| المصدر: |
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p515-517, 3p |
| مصطلحات موضوعية: |
T cells, REGULATORY T cells, ANTIGENS, T-cell exhaustion |
| مستخلص: |
SAR444245, a non-alpha IL2, rescues chronic antigen and CAR-driven T-cell dysfunction T cell dysfunction from chronic antigen stimulation limits the efficacy of T cell therapies. SAR444245 treatment of exhausted CD8 or CAR T cells restored functionality and alleviated T cell dysfunction. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
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