التفاصيل البيبلوغرافية
| العنوان: |
DISTINCT HODGKIN LYMPHOMA SUBTYPES IDENTIFIED BY NONINVASIVE GENOMIC PROFILING. |
| المؤلفون: |
Alig, S. K., Esfahani, M. Shahrokh, Garofalo, A., Li, M. Y., Rossi, C., Adams, R., Binkley, M. S., Jin, M. C., Olsen, M., Telenius, A., Mutter, J., Sworder, B. J., Schroers‐Martin, J., King, D. A., Schultz, A., Bögeholz, J., Su, S., Kathuria, K. R., Kang, X., Liu, C. L. |
| المصدر: |
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p96-98, 3p |
| مصطلحات موضوعية: |
HODGKIN'S disease, CIRCULATING tumor DNA, SOMATIC mutation |
| مستخلص: |
Since profiling of circulating tumor DNA (ctDNA) has shown utility in non-Hodgkin lymphoma genotyping and risk stratification, we employed a noninvasive approach in cHL to overcome challenges imposed by low tumor fractions. B Methods: b We profiled baseline plasma samples from 366 patients diagnosed with cHL, 99% of whom were enrolled prior to anti-lymphoma therapy. B Introduction: b The scarcity of malignant Reed-Sternberg cells has hampered comprehensive genomic profiling of classic Hodgkin lymphoma (cHL) as might inform personalized therapeutic strategies. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
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