دورية أكاديمية

Different prognostic outcomes in two cases of FDG-PET/CT-Positive and -negative cardiac angiosarcoma.

التفاصيل البيبلوغرافية
العنوان: Different prognostic outcomes in two cases of FDG-PET/CT-Positive and -negative cardiac angiosarcoma.
المؤلفون: Ryo Yamakuni, Shiro Ishii, Shoki Yamada, Junko Hara, Hiroki Suenaga, Shigeyasu Sugawara, Hirofumi Sekino, Takayoshi Yamaki, Keiichi Ishida, Yuko Hashimoto, Hiroshi Ito
المصدر: Fukushima Journal of Medical Science; 2023, Vol. 69 Issue 1, p45-49, 5p
مصطلحات موضوعية: CARDIAC arrest, ULTRASONIC imaging, ECHOCARDIOGRAPHY, CARDIAC catheterization, CANCER chemotherapy
مستخلص: Cardiac angiosarcoma is a rare malignant tumor with a poor prognosis, characterized by the high uptake of 18F-fluorodeoxyglucose (FDG). This case report presents two cases of cardiac angiosarcoma with a marked difference in FDG uptake and prognosis. Case Summary : Case 1 : A 40-year-old male presented with syncope. Ultrasound echocardiography demonstrated a cardiac tumor with a high uptake of 18F-FDG (maximum standardized uptake value=9.2). The patient underwent heart catheterization and tumor biopsy. The pathological result was high-grade angiosarcoma, and the MIB-1(Ki-67) proliferation index was approximately 20%. Systemic chemotherapy was administered ; however, the patient died 2 years and 5 months after disease onset. Case 2 : A 65-year-old female had a right atrial tumor incidentally diagnosed during routine ultrasound echocardiography. The tumor exhibited a low uptake of 18F-FDG (maximum standardized uptake value=1.8). Open heart surgery was performed, and the tumor was completely resected. Histological analysis revealed low-grade angiosarcoma, and the MIB-1(Ki-67) proliferation index was less than 5%. The patient was followed-up and had not relapsed 2 years after surgery. Conclusion : 18F-FDG uptake may reflect pathological tumor grade and prognosis in cardiac angiosarcoma. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00162590
DOI:10.5387/fms.2022-13