دورية أكاديمية
Serum Vitamin D Is Inversely Associated with Blood Eosinophil Count Among Adults with Allergic Asthma.
| العنوان: | Serum Vitamin D Is Inversely Associated with Blood Eosinophil Count Among Adults with Allergic Asthma. |
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| المؤلفون: | Daniel Hernández-Colín, Dante, Bedolla-Barajas, Martín, Morales-Romero, Jaime, Robles-Figueroa, Martín, Bedolla-Pulido, Angie, del Rosario Arroyo-Sánchez, Nora |
| المصدر: | Thoracic Research & Practice; Jul2023, Vol. 24 Issue 4, p208-213, 6p |
| مصطلحات موضوعية: | EOSINOPHILS, STATISTICS, ASTHMA, CONFIDENCE intervals, CROSS-sectional method, MULTIVARIATE analysis, MULTIPLE regression analysis, VITAMIN D, DESCRIPTIVE statistics, ALLERGIES, ODDS ratio, DATA analysis, DATA analysis software |
| مصطلحات جغرافية: | MEXICO |
| مستخلص: | OBJECTIVE: To evaluate the role that serum vitamin D concentration plays in the number of eosinophils in peripheral blood in adults with allergic asthma. MATERIAL AND METHODS: A total of 142 patients were categorized based on different cutoff points for eosinophils: =200, =300, =400, and =500 cells/mL. The vitamin D concentration was stratified into <20 and =20 ng/mL. The association between vitamin D (independent variable) and eosinophils (dependent variable) was explored using multivariate analysis. RESULTS: The average number of eosinophils in the included patients was 418 cells/mL, and 33.8% of the included patients had vitamin D concentrations =20 ng/mL. Asthmatic patients with vitamin D< 20 ng/mL had a higher mean concentration of eosinophils than did asthmatic patients with vitamin D =20 ng/mL (464 ± 377.7 eosinophils/mL vs. 327.8 ± 247.2 eosinophils/mL, P = .025). We also observed that vitamin D was inversely correlated with eosinophil count (rho = 0.244, P = .003). In the multivariate analysis, vitamin D <20 ng/mL showed a significant inverse association with each cutoff value for eosinophilia (odds ratio >1). CONCLUSION: Vitamin D concentrations <20 ng/mL are associated with a significant increase in the number of eosinophils in blood. Studies that analyze the use of vitamin D supplements as complementary therapy for the treatment of asthma are needed. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
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