دورية أكاديمية

Management of Functional Pancreatic Neuroendocrine Neoplasms.

التفاصيل البيبلوغرافية
العنوان: Management of Functional Pancreatic Neuroendocrine Neoplasms.
المؤلفون: Magi, Ludovica, Marasco, Matteo, Rinzivillo, Maria, Faggiano, Antongiulio, Panzuto, Francesco
المصدر: Current Treatment Options in Oncology; Jul2023, Vol. 24 Issue 7, p725-741, 17p
مستخلص: Opinion statement: Functional pancreatic neuroendocrine neoplasms (pNENs) are rare and heterogeneous diseases in terms of both clinical and pathological aspects. These tumors secrete hormones or peptides, which may cause a wide variety of symptoms related to a clinical syndrome. The management of functional pNENs is still challenging for clinicians due to the need to control both tumor growth and specific symptoms. Surgery remains the cornerstone in the management of local disease because it can definitively cure the patient. However, when the disease is not resectable, a broad spectrum of therapeutic options, including locoregional therapy, somatostatin analogs (SSAs), targeted therapies, peptide-receptor radionuclide therapy (PRRT), and chemotherapy, are available. The present review summarizes the main key issues regarding the clinical management of these tumors, providing a specific highlight on their therapeutic approach. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:15272729
DOI:10.1007/s11864-023-01085-0