التفاصيل البيبلوغرافية
| العنوان: |
Outcomes for oligometastatic head and neck cancer treated with stereotactic body radiotherapy: Results from an international multi‐institutional consortium. |
| المؤلفون: |
Id Said, Badr, Mutsaers, Adam, Chen, Hanbo, Husain, Zain A., Biswas, Tithi, Dagan, Roi, Erler, Darby, Foote, Matthew, Louie, Alexander V., Redmond, Kristin, Ricardi, Umberto, Sahgal, Arjun, Poon, Ian |
| المصدر: |
Head & Neck; Oct2023, Vol. 45 Issue 10, p2627-2637, 11p |
| مصطلحات موضوعية: |
HEAD & neck cancer, STEREOTACTIC radiotherapy, CONSORTIA, PROGRESSION-free survival, OVERALL survival |
| مستخلص: |
Background: We report the results of an international multi‐institutional cohort of oligometastatic (OMD) head and neck cancer (HNC) patients treated with SBRT. Methods: Patients with OMD HNC (≤5 metastases) treated with SBRT between 2008 and 2016 at six institutions were included. Treated metastasis control (TMC), progression‐free survival (PFS), and overall survival (OS) were analyzed by multivariable analysis (MVA). Results: Forty‐two patients with 84 HNC oligometastases were analyzed. The TMC rate at 1 and 2 years were 80% and 66%, with a median time to recurrence of 10.1 months. The median PFS and OS were 4.7 and 23.3 months. MVA identified a PTV point maximum (BED)10 > 100 Gy as a predictor of improved TMC (HR = 0.31, p = 0.034), and a cumulative PTV > 48 cc as having worse PFS (HR = 2.99, p < 0.001). Conclusion: Favorable TMC and OS was observed in OMD HNCs treated with SBRT. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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