دورية أكاديمية
Justification and demonstration through experimental test and literature, the main differances on coated and uncoated tablets.
العنوان: | Justification and demonstration through experimental test and literature, the main differances on coated and uncoated tablets. |
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المؤلفون: | Al Hasani, Mohammed K. Y., Ayvazian Davidian, Ana Maria |
المصدر: | Ajastan Kensabanakan Handes; 2023 Supplement, Vol. 75, p37-37, 2/3p |
مصطلحات موضوعية: | ODORS, EXPERIMENTAL literature, SOLID dosage forms, MEDICAL personnel |
مستخلص: | An important preface to any discussion on coating must be— Why coat tablets? Since a broad range of pharmaceutical oral solid dosage forms are coated, important reasons-include the following: 1. protecting the drug from its surrounding environment (particularly air, moisture, and light) to improve stability; 2.masking unpleasant taste and odor; 3. making it easier for the patient to swallow the product; 4. improving product identity, from the manufacturing plant, through intermediaries, and to the both healthcare workers and patients; 5. facilitating handling, particularly in high-speed packaging/filling lines, and automated counters in pharmacies, where the coating minimizes cross-contamination due to dust elimination; 6. improving product appearance, particularly where there are noticeable visible differences in tablet core ingredients from batch to batch; 7. reducing the risk of interaction between incompatible components. This would be achieved by using coated forms of one or more of the offending ingredients (particularly active compounds); 8. Improving product robustness because coated. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: | Complementary Index |
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