دورية أكاديمية
Transcriptome sequencing and microRNA–mRNA regulatory network construction in the lens from a Na2SeO3-induced Sprague Dawley rat cataract model.
العنوان: | Transcriptome sequencing and microRNA–mRNA regulatory network construction in the lens from a Na |
---|---|
المؤلفون: | Fang, Rui, Yue, Pei-Lin, Li, Hai-Long, Ding, Xue-Fei, Jia, Yu-Xuan, Liu, Zhao-Chuan, Zhou, Hong-Gang, Song, Xu-Dong |
المصدر: | BMC Ophthalmology; 11/16/2023, Vol. 23 Issue 1, p1-13, 13p |
مصطلحات موضوعية: | SPRAGUE Dawley rats, GENE expression, TRANSCRIPTOMES, POLYMERASE chain reaction, VISUAL perception |
مستخلص: | Background: A sight-threatening, cataract is a common degenerative disease of the ocular lens. This study aimed to explore the regulatory mechanism of age-related cataract (ARC) formation and progression. Methods: Cataracts in Sprague Dawley rats were induced by adopting the method that injected selenite subcutaneously in the nape. We performed high-throughput RNA sequencing technology to identify the mRNA and microRNA(miRNA) expression profiles of the capsular membrane of the lens from Na |
Copyright of BMC Ophthalmology is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
قاعدة البيانات: | Complementary Index |
كن أول من يترك تعليقا!