دورية أكاديمية
Deciphering the immune landscape of head and neck squamous cell carcinoma: A single-cell transcriptomic analysis of regulatory T cell responses to PD-1 blockade therapy.
العنوان: | Deciphering the immune landscape of head and neck squamous cell carcinoma: A single-cell transcriptomic analysis of regulatory T cell responses to PD-1 blockade therapy. |
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المؤلفون: | Miraki Feriz, Adib, Bahraini, Fatemeh, Khosrojerdi, Arezou, Azarkar, Setareh, Sajjadi, Seyed Mehdi, HosseiniGol, Edris, Honardoost, Mohammad Amin, Saghafi, Samira, Silvestris, Nicola, Leone, Patrizia, Safarpour, Hossein, Racanelli, Vito |
المصدر: | PLoS ONE; 12/14/2023, Vol. 18 Issue 12, p1-19, 19p |
مصطلحات موضوعية: | REGULATORY T cells, SQUAMOUS cell carcinoma, NOTCH signaling pathway, CETUXIMAB, PROGRAMMED cell death 1 receptors, IMMUNE checkpoint proteins, GENE expression, T cell receptors, T cells |
مستخلص: | Immunotherapy is changing the Head and Neck Squamous Cell Carcinoma (HNSCC) landscape and improving outcomes for patients with recurrent or metastatic HNSCC. A deeper understanding of the tumor microenvironment (TME) is required in light of the limitations of patients' responses to immunotherapy. Here, we aimed to examine how Nivolumab affects infiltrating T |
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قاعدة البيانات: | Complementary Index |
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