دورية أكاديمية
The In Vitro Inhibitory Activity of Pacaya Palm Rachis versus Dipeptidyl Peptidase-IV, Angiotensin-Converting Enzyme, α-Glucosidase and α-Amylase.
| العنوان: | The In Vitro Inhibitory Activity of Pacaya Palm Rachis versus Dipeptidyl Peptidase-IV, Angiotensin-Converting Enzyme, α-Glucosidase and α-Amylase. |
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| المؤلفون: | Bernardino-Nicanor, Aurea, Fernández-Avalos, Stephanie, Juárez-Goiz, José Mayolo Simitrio, Montañez-Soto, José Luis, González-Cruz, Leopoldo |
| المصدر: | Plants (2223-7747); Feb2024, Vol. 13 Issue 3, p400, 13p |
| مصطلحات موضوعية: | ALPHA-glucosidases, ANGIOTENSIN converting enzyme, PALMS, CHRONIC diseases, HYPERGLYCEMIA, INFLORESCENCES |
| مصطلحات جغرافية: | CENTRAL America, MEXICO |
| مستخلص: | The pacaya palm (Chamaedorea tepejilote Liebm) is an important food that is commonly consumed in Mexico and Central America due to its nutritive value. It is also used as a nutraceutical food against some chronic diseases, such as hypertension and hyperglycemia. However, few reports have indicated its possible potential. For this reason, the goal of this research was to evaluate the effects of the enzymatic activity of the pacaya palm inflorescence rachis on both hypertension and hyperglycemia and the effects of thermal treatments on the enzymatic activity. The enzymatic inhibition of ACE (angiotensin-converting enzyme), DPP-IV (dipeptidyl peptidase-IV), α-glucosidase and α-amylase were evaluated, all with powder extracts of pacaya palm inflorescences rachis. The results indicated that thermally treated rachis showed increased enzymatic inhibitory activity against α-amylase and DPP-IV. However, all rachis, both with and without thermal treatment, showed low- or no enzymatic activity against α-glucosidase and ACE. Apparently, the mechanism of action of the antidiabetic effect of rachis is mediated by the inhibition of α-amylase and DPP-IV and does not contribute with a significant effect on enzymes involved in the hypertension mechanism. Finally, the properties of the extract were modified via the extraction method and the temperature tested. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: | Complementary Index |
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