دورية أكاديمية

Collagenous Colitis with Escitalopram Use: A Case Report and Literature Review.

التفاصيل البيبلوغرافية
العنوان: Collagenous Colitis with Escitalopram Use: A Case Report and Literature Review.
المؤلفون: Gray, Emily, Wettergreen, Sara A.
المصدر: Healthcare (2227-9032); Feb2024, Vol. 12 Issue 3, p330, 7p
مصطلحات موضوعية: COLITIS diagnosis, CITALOPRAM, DIARRHEA, COLONOSCOPY, ORAL drug administration, DIFFERENTIAL diagnosis, MENTAL depression, OMEPRAZOLE, COLITIS, ABDOMINAL pain, BUDESONIDE
مستخلص: We present the case of a 42-year-old female whose escitalopram use potentially contributed to a diagnosis of collagenous colitis. The patient presented with significant watery, nonbloody diarrhea, abdominal cramping and pain, and weight loss. Established risk factors of microscopic colitis in this patient include a history of smoking and female gender. The patient underwent a colonoscopy, which confirmed histological changes consistent with collagenous colitis. Prescribed therapy included oral budesonide and omeprazole, continued for eight and twelve weeks, respectively. Escitalopram was continued, with a discussion regarding changing to an alternative therapy. Based on the patient's history of escitalopram use, this case suggests a relationship between escitalopram and microscopic colitis. Though case reports of patients diagnosed with microscopic colitis after antidepressant use are published, this case appears to be the only report of collagenous colitis without macroscopic complications following escitalopram use. This case adds further support in that antidepressants may contribute to microscopic colitis. Despite an undefined frequency of association, healthcare providers who prescribe antidepressants should be cognizant of the theorized association and understand risk factors, screening, and treatment approaches. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:22279032
DOI:10.3390/healthcare12030330