التفاصيل البيبلوغرافية
| العنوان: |
DYSLIPIDEMIA AND CARDIOVASCULAR CHANGES IN CHRONIC KIDNEY DISEASE. |
| المؤلفون: |
Manoraju, Katepogu, Kumar, B. Kishore, Somappa, K., Srinivasulu, Damam |
| المصدر: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 1, p272-281, 10p |
| مصطلحات موضوعية: |
CHRONIC kidney failure, DYSLIPIDEMIA, KIDNEY diseases, PUBLIC hospitals, CHRONICALLY ill |
| مستخلص: |
INTRODUCTION This study was carried out to assess the lipid profile and cardiovascular complications in patients with chronic kidney disease. METHODS This was a cross-sectional study carried out over a period of 2 years involving 60 patients with chronic kidney disease who were admitted to the Government General Hospital at Kurnool. Patients with bilaterally contracted kidneys, those with a GFR < 60 mL/min/1.73m² and adults aged > 18 years with a history of kidney disease for a duration of > 6 months were included in the study. RESULTS The mean total cholesterol of overall patients was 189.8 ± 14.72 mg/dl. The mean total cholesterol was significantly higher in patients with stage 5 CKD compared to stage 4 and stage 3 CKD patients. (p < 0.05; significant). The mean triglycerides of overall patients were 174.8 ± 16.29 mg/dl. There was no significant difference in mean triglycerides between different stages of CKD patients. (p > 0.05; not significant). The mean HDL-cholesterol of overall patients was 37.50 ± 7.56 mg/dl. There was no significant difference in mean HDL-cholesterol between different stages of CKD patients. (p>0.05; not significant). The mean LDL-cholesterol of overall patients was 132.2 ± 15.74 mg/dl. There was no significant difference in mean LDL-cholesterol between different stages of CKD patients. (p>0.05; not significant). The mean VLDL-cholesterol of overall patients was 37.50 ± 12.36 mg/dl. There was no significant difference in mean VLDLcholesterol between different stages of CKD patients. (p > 0.05; not significant). CONCLUSION CKD continues to be a major disease affecting males in the age group of 41 to 50 years. Dyslipidemia in the form of higher cholesterol and triglyceride levels and cardiovascular changes are observed more frequently in CKD patients, especially in stages 4 and 5. Further research is warranted towards mitigating these important risk factors in order to reduce mortality in this cohort of patients. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
